Multivitamins
9.5
Immunity support
Most Useful Review
Vitamin C with bioflavonoids enhances the efficacy of vitamin C. I take it with collagen. During colds and acute respiratory infections, I consume 500 mg every 2-3 hours. Vitamin C is crucial for immunity as it boosts white blood cell production and enhances neutrophils' ability to combat viruses. It's a fundamental antioxidant necessary for blood clotting and the synthesis of collagen and connective tissues.
9.5
Pain relief achieved
Most Useful Review
I highly recommend these vitamins for joints. I suffered from a cold leg for a prolonged period, which led to knee pain. Doctors prescribed chondroprotectors, but they did nothing and even worsened my condition. However, an athlete suggested a regimen that worked wonders. My knee pain stopped entirely, and I feel great. Although doctors diagnosed me with arthritis and arthrosis, I suspect they were mistaken. After following the regimen of taking one can for over a month, with breaks, I believe it significantly aids my joints. This scheme is fantastic for me, and I feel wonderful.
Spirulina
9.5
Prevented colds effectively
Most Useful Review
After much research, I started taking Spirulina and shared it with my family. It's effective; we haven't had any colds this year, and it helps maintain a healthy digestive system.
10
Prevention and value
Most Useful Review
Spirulina is a fantastic algae supplement that helps in the fight against colds. I appreciate its quality and affordability compared to other brands, plus it's completely organic. It has been beneficial for preventive health.
Childrens Cold Flu Cough
9.5
Improves cold symptoms
Most Useful Review
Works for everything! I stocked up on this elderberry syrup for colds, and for good reason! In September, ARVI struck and my baby caught it. I started giving this syrup from the first day of the cold, and the condition improved immediately; the snot and sneezes just went away, and the child did not become ill further, although it typically takes five days. The syrup tastes pleasant and sweet, my child drinks it without complaints at just 1.5 years old. The ingredients are all natural, and there have been no allergies. I’m very pleased with the quality of this product, and it’s now always in stock at home!
9.5
Rapid cold relief
Most Useful Review
This syrup is miraculous! I'm thrilled with my purchase! It helps us every time. As soon as the first signs of a cold appear, I immediately give it, and my baby already feels significantly better. I will definitely buy this syrup again! It tastes good, smells like elderberry, and my child drinks it joyfully.
Echinacea
10
Effective for cold
Most Useful Review
I constantly order this echinacea and have recommended it to many friends and family. At the first sign of a cold, we take it, and it either alleviates the illness or makes it much easier to handle. The large jar contains 250 capsules, which is sufficient for our big family for quite some time. My children, aged 9 and 15, have no trouble taking them as the capsules are small and easy to swallow. Highly recommended.
9.5
Prevents colds
Most Useful Review
Excellent value for money! I have been using this echinacea for cold prevention during the season. I've tried other brands but notice no difference; I just choose whichever is available. As soon as I feel the slightest symptoms of a cold, I begin taking it, and it truly saves me from becoming ill. It effectively promotes recovery.
Fiber
9.5
Immune support
Most Useful Review
This is what I drink constantly, and during a cold, I increase the dosage to 2-3 capsules per day. It helps a lot and the results are almost immediate. My immune system feels strengthened.
9.5
Less frequent colds
Most Useful Review
After regularly taking vitamin D3, I’ve noticed that both my child and I rarely catch a cold. My daughter used to attend kindergarten without a break from October to February, but now, she’s far healthier. I generally feel more cheerful as well. When I stop taking vitamin D3, I often experience discomfort in my back, but as soon as I resume, the pain disappears almost immediately. This improvement truly delights me.
Probiotics
9.5
No colds experienced
Most Useful Review
Excellent! I had no side effects or nausea while taking these on an empty stomach. During the course, I discontinued sedatives, as these vitamins effectively replaced them, helping me stay calm. Plus, I experienced no colds. I plan to repeat this with pleasure.
9.5
No winter colds
Most Useful Review
I appreciated the composition of these vitamins, as I sought a replacement for the discontinued teenage vitamins – these are perfect. Additionally, we consumed vitamin D throughout winter, and over the past six months, not a single cold, especially during such a hectic period! I believe these vitamins nicely complement the limited diet of a very selective teenager.
N Acetyl Cysteine Nac
9
N-acetylcysteine protects cold platelets
The effect of modulating platelet reactive oxygen species by the addition of antioxidants to prevent clearance of cold-stored platelets.
Most Relevant Research
We explored the impact of N-acetylcysteine, an antioxidant, on the preservation of cold-stored platelets. The study focused on understanding how this treatment might reduce the harmful effects caused by reactive oxygen species (ROS) generated during cold storage.
Platelet concentrates were categorized into three groups: those stored at room temperature, those kept cold, and those cold-stored with added N-acetylcysteine at varying concentrations. After five days of storage, we measured ROS production, lipid peroxidation, platelet activation, and other quality indicators.
Our findings highlighted that N-acetylcysteine effectively diminished the production of ROS, thus protecting the cold-stored platelets from damage and premature clearance by the immune system in both lab settings and live models. Importantly, using the right amount of N-acetylcysteine significantly improved the survival of these platelets in circulation.
Overall, this study sheds light on the potential benefits of incorporating antioxidants in platelet storage practices to enhance their functionality and longevity.
Platelet concentrates were categorized into three groups: those stored at room temperature, those kept cold, and those cold-stored with added N-acetylcysteine at varying concentrations. After five days of storage, we measured ROS production, lipid peroxidation, platelet activation, and other quality indicators.
Our findings highlighted that N-acetylcysteine effectively diminished the production of ROS, thus protecting the cold-stored platelets from damage and premature clearance by the immune system in both lab settings and live models. Importantly, using the right amount of N-acetylcysteine significantly improved the survival of these platelets in circulation.
Overall, this study sheds light on the potential benefits of incorporating antioxidants in platelet storage practices to enhance their functionality and longevity.
9.5
Prevents bronchitis
Most Useful Review
I was sceptical about this Life Extension N-Acetyl-L-Cysteine (NAC) given other brands I'd had. However, it worked as hoped during my cold, preventing bronchitis. As someone with early emphysema and COPD, I use it at the first sign of a cold to avoid doctor visits. This will be my go-to NAC, as it’s effective and reasonably priced.
L Lysine
9
Lysine aids cold adaptation mechanisms
Cold exposure accelerates lysine catabolism to promote cold acclimation via remodeling hepatic histone crotonylation.
Most Relevant Research
We set out to uncover how certain amino acids, particularly lysine, help with cold acclimation. Over three months, 20 men were monitored for physiological changes after being exposed to cold.
We found that continuous exposure led to faster cold-induced vasodilation and improved finger temperature. Notably, lysine was the only amino acid that significantly changed and positively correlated with these improvements in cold response.
In mouse trials, lysine supplementation helped maintain core body temperature during cold exposure, indicating its role in supporting metabolic adjustments to the cold.
We found that continuous exposure led to faster cold-induced vasodilation and improved finger temperature. Notably, lysine was the only amino acid that significantly changed and positively correlated with these improvements in cold response.
In mouse trials, lysine supplementation helped maintain core body temperature during cold exposure, indicating its role in supporting metabolic adjustments to the cold.
9.5
Miracle remedy
Most Useful Review
Best Amino Acid!!! Vitamins work. I’ve had more than five colds and cold sores in the past! This is a miracle remedy! From the very first days, I experience a surge of energy, need less sleep, and my general well-being improves. Scratches and bruises heal better, and my immunity has strengthened. I highly recommend this amino acid!
Oregano Oil Supplements
10
Powerful relief
Most Useful Review
Excellent! This oil is a powerful kitchen staple. Just three drops on an empty stomach can eliminate all cold symptoms and even throat and stomach pain. Following Dr. Salah Al-Rashed’s advice, the quality is unmatched and the taste, while strong, is tolerable.
9.5
Children's colds remedy
Most Useful Review
The quality is excellent. I take 2 to 3 drops under my tongue if I feel tired, and the results are astonishing. I’ve used it on my children; when they show cold symptoms, it works effectively, cooling them down, and in less than a day, they feel better. I also used it for my mother's gum inflammation, and she found immediate relief. This product is worth every penny.
Vitamins
9
Vitamin A's key role in thermogenesis
Intact vitamin A transport is critical for cold-mediated adipose tissue browning and thermogenesis.
Most Relevant Research
We explored how vitamin A affects our body’s response to cold, specifically looking at its role in transforming white fat into brown fat, a process known as browning. This transformation is significant, as it can help reduce obesity and improve metabolic health.
In our investigation, we conducted cold exposure studies involving both mice and humans. We observed that exposure to cold led to an increase in circulating vitamin A, also known as retinol, and its transporter protein, Rbp. However, in mice lacking this protein, we found that their ability to adapt to the cold and promote thermogenesis—essentially, generating heat through fat—was severely compromised.
Interestingly, we also noted that stimulating human fat cells with retinol heightened the expression of genes associated with thermogenesis and boosted mitochondrial activity, which is vital for burning fat. In humans, the rise in vitamin A during cold exposure hinted at improved fat utilization.
Overall, our findings revealed that not only are vitamin A levels responsive to cold, but effective transportation of this vitamin is crucial for cold-induced fat browning and the body's ability to generate heat.
In our investigation, we conducted cold exposure studies involving both mice and humans. We observed that exposure to cold led to an increase in circulating vitamin A, also known as retinol, and its transporter protein, Rbp. However, in mice lacking this protein, we found that their ability to adapt to the cold and promote thermogenesis—essentially, generating heat through fat—was severely compromised.
Interestingly, we also noted that stimulating human fat cells with retinol heightened the expression of genes associated with thermogenesis and boosted mitochondrial activity, which is vital for burning fat. In humans, the rise in vitamin A during cold exposure hinted at improved fat utilization.
Overall, our findings revealed that not only are vitamin A levels responsive to cold, but effective transportation of this vitamin is crucial for cold-induced fat browning and the body's ability to generate heat.
9.3
Mild illness experience
Most Useful Review
I bought this for my three-year-old son, especially appreciating the liquid form. Previously, he was often ill and missed a lot of kindergarten. For the second year, we've been boosting his immune system with these products. We rarely fall ill now, and if we do, it’s usually mild. At the first sign of a cold, I give a triple dose. Vitamin C certainly strengthens his immune system, and he enjoys the sweet and sour taste.
Enzymes
8
Nattokinase aids cold recovery
A single dose of oral nattokinase accelerates skin temperature recovery after cold water immersion: A double-blind, placebo-controlled crossover study.
Most Relevant Research
We conducted a study to explore how a single dose of nattokinase (NK) influences recovery of skin temperature after exposure to cold water. This double-blind, placebo-controlled crossover study involved nine healthy men who took either NK or a placebo before submerging their hands in ice-cold water at 10 °C for one minute.
Our findings showed that participants who took NK experienced a quicker recovery of skin temperature in their middle finger, palm, and back of the hand compared to those who took the placebo. Although cold exposure initially caused a significant drop in skin temperature, the NK appeared to accelerate the warming process afterward.
Interestingly, we did not observe any changes in heart rate, cardiac output, or sympathetic nervous activity as a result of taking NK. This is noteworthy because it suggests that while NK may help with temperature recovery, it does not impact certain cardiovascular responses typically associated with cold exposure.
Overall, our study highlights the potential benefits of nattokinase, especially for individuals who are more sensitive to cold, such as women and the elderly. It could offer a new avenue for managing cold sensitivity and minimizing excessive vasoconstriction during chilly conditions.
Our findings showed that participants who took NK experienced a quicker recovery of skin temperature in their middle finger, palm, and back of the hand compared to those who took the placebo. Although cold exposure initially caused a significant drop in skin temperature, the NK appeared to accelerate the warming process afterward.
Interestingly, we did not observe any changes in heart rate, cardiac output, or sympathetic nervous activity as a result of taking NK. This is noteworthy because it suggests that while NK may help with temperature recovery, it does not impact certain cardiovascular responses typically associated with cold exposure.
Overall, our study highlights the potential benefits of nattokinase, especially for individuals who are more sensitive to cold, such as women and the elderly. It could offer a new avenue for managing cold sensitivity and minimizing excessive vasoconstriction during chilly conditions.
10
Circulation improvement
Most Useful Review
I bought this for my husband's cold left foot, which he couldn't feel for years. Within 24 hours of taking it, he regained feeling, and it felt warm again! He had thought he would suffer forever. Now, he’s active and claims he has his life back—his hands are warm too. He takes one capsule in the morning and another before dinner. We ordered multiple bottles to keep this up. We're incredibly grateful for this product!
Childrens Herbs
9
Effective for colds
Most Useful Review
I ordered this on my doctor's recommendation, as I heard elderberry is effective at the first sign of a cold, and it truly helps you get back on your feet. I recommend everyone to purchase it.
9.5
Quick recovery
Most Useful Review
I strongly advise this for parents of children who frequently fall ill during winter. It helps them recover quickly and boosts their immunity. It’s also great for colds and other ailments. Unfortunately, it's no longer available at iHerb, and I didn't place a new order in time. If you found this helpful, please give me a like.
Face Moisturizers Creams
8.8
Fights flaking well
Most Useful Review
An excellent cream, especially for winter, it protects skin from the cold and combats flaking effectively.
9.5
Prevents wind damage
Most Useful Review
I think this cream is very good. I use it to keep the harsh cold wind from damaging my face. Its quality and texture are fantastic, hydrating while retaining moisture well. I liked it and recommend it as a substitute for Nivea’s blue can.
Elderberry Sambucus
7
Effectiveness of Vitamin C on Colds
Vitamin C for the common cold and pneumonia.
Most Relevant Research
We explored the effects of vitamin C on the common cold and pneumonia by examining a range of studies. Interestingly, research on animals suggests that vitamin C may have protective effects against infections. However, when it comes to preventing colds in the general population, taking more than 1 gram of vitamin C per day didn’t show significant benefits.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
9.5
Immunity boost proven
Most Useful Review
I always keep a jar of these lozenges in reserve, as they are crucial at the first sign of a cold. They contain only herbal ingredients and have a pleasant elderberry flavour that dissolves quickly. With zinc and vitamin C, my immunity increases. I recommend purchasing these.
L Glutamine
9.5
Stopped getting sick
Most Useful Review
Great. Since I began taking one capsule daily, I've stopped getting sick. Although my family caught a cold, I did not. I highly recommend it.
10
Covid recovery aid
Most Useful Review
I highly recommend Glutamine! It played a crucial role in my recovery from a severe covid experience, preventing fever, body aches, and weakness. It effectively combats unpleasant effects during colds, and I always take it with meals to ward off sickness.
Garlic
9
Efficacy of garlic against colds
Interventions for preventing influenza: An overview of Cochrane systematic reviews and a Bayesian network meta-analysis.
Most Relevant Research
We examined the effectiveness of garlic as a treatment to prevent cold symptoms based on a comprehensive review of systematic reviews. This analysis included various studies that compared garlic and other preventative interventions against a control group receiving no treatment or a placebo.
Our findings indicated that garlic demonstrated notable advantages in reducing instances of influenza, a key player in the spectrum of cold-like illnesses. However, we also learned that the evidence surrounding garlic specifically for cold prevention isn't robust enough to make definitive claims.
It's essential to note that while garlic showed potential, vitamin C did not present any significant benefits in this context. Ultimately, the effectiveness of other interventions remains to be convincingly validated with strong scientific evidence.
Our findings indicated that garlic demonstrated notable advantages in reducing instances of influenza, a key player in the spectrum of cold-like illnesses. However, we also learned that the evidence surrounding garlic specifically for cold prevention isn't robust enough to make definitive claims.
It's essential to note that while garlic showed potential, vitamin C did not present any significant benefits in this context. Ultimately, the effectiveness of other interventions remains to be convincingly validated with strong scientific evidence.
9.5
Strong immunity
Most Useful Review
It helps immensely. No colds, strong immunity. It is completely odourless and does not cause any disorders or bloating. Overall, this supplement does not have the negative aspects typically associated with garlic. It has helped me maintain a prolonged period without serious colds.
Potassium
9.5
Less PMS swelling
Most Useful Review
The capsules are easy to take and I prefer them to the potassium sold on Amazon, which requires many tablets. I bought B-1 and potassium to manage PMS before my period. Since starting the potassium, my swelling has significantly decreased. I've found this potassium more effective than other options.
8.8
Puffy eyes fine
Most Useful Review
I take one pill each night. Before this, I woke with swollen and puffy eyelids, but they have improved since starting the treatment. Previously, I hadn’t noticed any benefit from potassium supplements, so I’m really pleased with this purchase. It might be a coincidence since it's cold, but sometimes I wake at 4am needing the bathroom.
Turmeric Curcumin
10
Quick cold relief
Most Useful Review
Great! Feel free to take it; the worker does everything perfectly. It prevents illness, as my cold sore vanished completely within three days. In such instances, I take one capsule in the morning and evening or at lunchtime with food. Usually, just one capsule in the morning suffices, taken with food.
9.5
Prevention effectiveness
Most Useful Review
Recommend! The entire family used it for prevention, my mother’s joint pain ceased, and colds were avoided. I’ll purchase more.
5 Htp
9.5
Cold protection
Most Useful Review
I have been using vitamins for the past month, and I can confirm they work! My back and neck aches are gone. I felt a cold wind, but after taking vitamins, I didn't even notice it. Recently, my knees were throbbing so badly I had to go to hospital! My friends also said they noticed a difference.
9.5
Immune support
Most Useful Review
Hello everyone! I trust the supplements from this brand! I've tried various ones, and they are of excellent quality at a nice price. I purchased this product for immune support during colds, and it performs this task perfectly. The packaging is convenient, with a tightly closing lid. The capsules are standard size and easy to use.
Resveratrol
9.5
Improved cold symptoms
Most Useful Review
Super strong antioxidants assist with cardiovascular issues and significantly improve colds and nasal allergies. I used to suffer from a severe runny nose due to weather changes, using a roll of paper daily. After taking resveratrol for about a week, the runny nose has not returned. Both my physical strength and mentality have become more robust. I find that I can achieve better results during exams after taking two capsules beforehand. If you're prone to illness, it helps boost immunity. Recently, when I had a fever that lasted three days, I took 8 tablets a day and felt better the next day. Amazing, isn't it?
9.5
No cold sores
Most Useful Review
GOOD STUFF! I used to get cold sores every other month for years. I began using this with glyconutrient in November 2008 and haven't experienced even a hint of a cold sore since. My immune system is the best it's ever been.
Selenium
9.5
Cold symptom relief
Most Useful Review
I find this selenium supplement effective. When I feel the onset of a cold, I take it alongside zinc and vitamins C and D in higher doses, and by morning, I already feel well. Iodine needs selenium as a cofactor, which is beneficial for overall health.
9.5
Prevents colds efficiently
Most Useful Review
My husband and I took this product along with zinc, vitamin D, and magnesium throughout autumn, and we didn't fall ill. The capsules are pleasantly small, with a specific smell that's not off-putting, and easy to swallow. Very effective for staying healthy and preventing colds.
Beta Glucan
9.5
Clear difference noted
Most Useful Review
Best! Very satisfied 👍 I don't think there's a product like this during such a difficult time due to COVID-19. I noticed a clear difference when I took it compared to when I didn't. When I have a cold with a sore throat or runny nose, I take 4 tablets – 2 each morning and evening on an empty stomach. In the morning, I eat it with lactic acid bacteria, which enhance its effects. Evenings are before bed. I regret the day I forgot to take this, as I felt unwell. I wish I'd discovered it sooner. The egg-sized tablets are easy to swallow, with no strange odour. Good quality at a low price; I bought 6 bottles and will definitely repurchase after finishing them. I highly recommend it!
9.5
Maintains health
Most Useful Review
Excellent! This formula truly works. You won't notice immediate changes, but one day you'll realise you're consistently healthy—as colds and viruses will no longer disrupt your life. Give it a try and see for yourself!
Barley Grass
9.5
No flu or cold
Most Useful Review
I cannot imagine my life without this greens product! It is simply the best—I have increased energy, better skin, and my hair is thriving. Since I started drinking it in April 2006, I haven't faced a single cold or flu.
9.5
Indispensable health
Most Useful Review
I've been drinking this for years, always having it every morning. The ingredients are of great quality! This superfood fills the gaps in my diet and tastes delightful. Since using it, I've managed to avoid colds and illness. It's essential for our health, and my whole family loves it! Highly recommended.
Tea Tree Oil
9.3
Strengthens immunity
Most Useful Review
The oil has a strong aroma. I add 5 drops to an oil spray, filling the room with its scent! I also use it for oral hygiene, dripping a few drops on my toothbrush. It’s an excellent antiseptic and anti-inflammatory agent, supporting the fight against colds while boosting the immune system. Highly recommend!
9.5
Excellent for colds
Most Useful Review
This amazing oil is truly brilliant. It has a strong smell and numerous beneficial properties. It can be used in a humidifier for air disinfection and for gargling at the first hint of a cold. It’s also excellent for skin, providing a smoother complexion. The aroma promotes relaxation, making it great for sleep. I find it a salvation for colds, as I smear it in my nose to combat bacteria.
Homeopathy
9.5
Remarkable results
Most Useful Review
I tried homeopathy for the first time and was amazed by the results! My daughter exhibited the early signs of a cold, and after taking the remedy, she was fine by the next day. I've ordered it twice now and will continue to do so.
9.5
First sign remedy
Most Useful Review
This is genuinely effective at the first sign of a cold.
Calcium Magnesium
9
Magnesium enhances vascular preservation
Low Calcium-High Magnesium Krebs-Henseleit Solution Combined with Adenosine and Lidocaine Improved Rat Aortic Function and Structure Following Cold Preservation.
Most Relevant Research
We examined the effectiveness of modified Krebs-Henseleit (KH) solutions with low calcium and high magnesium levels on preserving vascular function during cold storage. Our focus was on whether adding adenosine and lidocaine could further improve the preservation of rat aortic rings after six days of cold preservation.
In our study, we found that traditional preservation solutions often fail to maintain proper vascular function after just three days of cold storage. However, when we tested a modified KH solution with lower calcium and higher magnesium, we observed significant recovery of contraction and relaxation functions in the aortic rings. This suggests that magnesium plays a vital role in preserving these functions.
Interestingly, while adding adenosine and lidocaine did not enhance contraction, it did improve the aortic rings' ability to relax in response to a chemical called acetylcholine. Furthermore, a histological examination showed that the addition of adenosine positively affected the endothelial lining and structural integrity of the vessels, highlighting its importance in cold preservation.
Overall, our findings suggest that magnesium in combination with adenosine significantly enhances the preservation of vascular structures and functionalities during extended cold storage, making it an important consideration for vascular grafts.
In our study, we found that traditional preservation solutions often fail to maintain proper vascular function after just three days of cold storage. However, when we tested a modified KH solution with lower calcium and higher magnesium, we observed significant recovery of contraction and relaxation functions in the aortic rings. This suggests that magnesium plays a vital role in preserving these functions.
Interestingly, while adding adenosine and lidocaine did not enhance contraction, it did improve the aortic rings' ability to relax in response to a chemical called acetylcholine. Furthermore, a histological examination showed that the addition of adenosine positively affected the endothelial lining and structural integrity of the vessels, highlighting its importance in cold preservation.
Overall, our findings suggest that magnesium in combination with adenosine significantly enhances the preservation of vascular structures and functionalities during extended cold storage, making it an important consideration for vascular grafts.
9.5
Cold sensitivity reduced
Most Useful Review
Initially, I was troubled by tooth sensitivity, particularly to cold food. However, after commencing this vitamin course, I saw a marked reduction in sensitivity after about 10 days. I'm pleased to report that it has now completely resolved.
Evening Primrose Oil
9.5
Improved sleep quality
Most Useful Review
A wonderful remedy for women over 45-50 who struggle with menopause! My mother was exhausted before this medication, suffering from constant sweating and mood instability. After taking these pills for a week and a half, she felt noticeably better, sleeping well at night! I have been buying them for over a year now and would recommend them to anyone. The packaging is also good, ensuring nothing breaks during delivery. Stay healthy!
8.8
Effective menopause remedy
Most Useful Review
An excellent remedy for women experiencing menopause! My mother, who is over 45-50 years old, was unable to cope with menopause, suffering from sleep disturbances and constant sweating. After purchasing these pills for her, she felt a significant improvement in just a week and a half! She now sleeps through the night without issue. For the last six months, I’ve been buying them consistently and recommending them widely! The delivery was flawless, and the jar is well-packed. Stay healthy!
Vitamin B Complex
9.5
Immediate cold relief
Most Useful Review
If you can take advantage of the active form of vitamin at an affordable price, please do! When my head cold was prolonged, it was healed immediately after taking it twice a day. I highly recommend the active form mentioned here.
9.5
Strengthened immunity
Most Useful Review
For me, they were effective. I purchased vitamins to bolster my immunity after pregnancy and two years of breastfeeding. My body was exhausted, and I often suffered from colds. After taking these vitamins, I felt a surge of energy and strength, and throughout the winter, I didn't experience any ARI.
Ubiquinol Coq10
NOW Foods Ubiquinol
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 12 Reviews
8.8
9.5
No colds experienced
Most Useful Review
I drank two packs - for the whole autumn, I NEVER got sick. There was not even a banal runny nose. Even in summer, I had no colds, despite often getting my feet wet in the rain. There was less 'pull' in my heart area, with unpleasant sensations a couple of times a week, but I haven't noticed them lately.
10
No more colds
Most Useful Review
Great product! I have been taking this ubiquinol for a long time, as I trust the manufacturer. I use it to maintain my health, and it has really helped. I've stopped getting colds and viral illnesses entirely, and I believe this antioxidant is responsible for it.
Childrens Homeopathy
10
Effective for colds
Most Useful Review
Wonderful! Just mega gorgeous! This is a miracle syrup! As soon as a cold begins, it is essential to apply the remedy. The syrup has a lovely composition, with no chemicals, and it’s pleasant. Most importantly - it works really quickly! Just what I need for the winter!
9.5
Essential for children
Most Useful Review
Excellent and effective for colds. Every home with children should have this on hand.
Homeopathy Formulas
9.5
Heals cold quickly
Most Useful Review
Remedy, amazing! This medicine is also inexpensive, as it effectively treats a cold. I took it four times within the first hour, and I was already feeling better. Fantastic!
10
Highly effective remedy
Most Useful Review
A very effective product that I've ordered 10 times, suitable for both children and adults. It quickly alleviates colds and their symptoms. I use it for my children aged 3, 5, and 16, and they tolerate its pleasant taste well. It's of high quality and contains absolutely safe ingredients, with enough for the entire season.
Olive Leaf
9.5
Excellent cold remedy
Most Useful Review
At the first sign of a cold, if I take olive leaf immediately, it remarkably helps me avoid getting sick. Often, all my symptoms disappear by the third day, leaving me feeling healthy. Unlike traditional antibiotics, the olive leaf effectively combats both bacterial and fungal infections in the body.
9.5
Cold preparedness
Most Useful Review
This product is always in my first aid kit, as it effectively inhibits viruses and bacteria that cause colds.
Magnesium
9
Magnesium enhances vascular preservation
Low Calcium-High Magnesium Krebs-Henseleit Solution Combined with Adenosine and Lidocaine Improved Rat Aortic Function and Structure Following Cold Preservation.
Most Relevant Research
We examined the effectiveness of modified Krebs-Henseleit (KH) solutions with low calcium and high magnesium levels on preserving vascular function during cold storage. Our focus was on whether adding adenosine and lidocaine could further improve the preservation of rat aortic rings after six days of cold preservation.
In our study, we found that traditional preservation solutions often fail to maintain proper vascular function after just three days of cold storage. However, when we tested a modified KH solution with lower calcium and higher magnesium, we observed significant recovery of contraction and relaxation functions in the aortic rings. This suggests that magnesium plays a vital role in preserving these functions.
Interestingly, while adding adenosine and lidocaine did not enhance contraction, it did improve the aortic rings' ability to relax in response to a chemical called acetylcholine. Furthermore, a histological examination showed that the addition of adenosine positively affected the endothelial lining and structural integrity of the vessels, highlighting its importance in cold preservation.
Overall, our findings suggest that magnesium in combination with adenosine significantly enhances the preservation of vascular structures and functionalities during extended cold storage, making it an important consideration for vascular grafts.
In our study, we found that traditional preservation solutions often fail to maintain proper vascular function after just three days of cold storage. However, when we tested a modified KH solution with lower calcium and higher magnesium, we observed significant recovery of contraction and relaxation functions in the aortic rings. This suggests that magnesium plays a vital role in preserving these functions.
Interestingly, while adding adenosine and lidocaine did not enhance contraction, it did improve the aortic rings' ability to relax in response to a chemical called acetylcholine. Furthermore, a histological examination showed that the addition of adenosine positively affected the endothelial lining and structural integrity of the vessels, highlighting its importance in cold preservation.
Overall, our findings suggest that magnesium in combination with adenosine significantly enhances the preservation of vascular structures and functionalities during extended cold storage, making it an important consideration for vascular grafts.
9.5
Coincidental improvement
Most Useful Review
This magnesium is excellent and of high quality. I have consumed it for a short time and have already noticed a boost in my immune system. I fell ill with a viral infection, likely the prevalent virus of 2020, but I recovered almost without noticing. A slight stuffy nose and general weakness were my symptoms, which faded in just 2 days! Previously, my colds lasted longer. I did increase my zinc intake during these days, and as soon as I could, I went straight back to my gym, discovering that my strength hadn’t diminished and there was no lingering weakness! I’m unsure if it’s a coincidence, but overall, I’m happy with this supplement.
Lotion
Curel Ultra Healing
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 12 Reviews
8.8
9.5
Amazing for winter
Most Useful Review
It's fantastic, truly! It deserves a million stars for its deep moisture. I’ve tried it in the cold winter, and it keeps my skin feeling lovely. It doesn't irritate my skin and works well for eczema. The size is great, it lasts long, and the quality is exceptional. It has a subtle lemon scent that I quite like.
9
Wonderful hydration
Most Useful Review
I purchased this based on Abdul Majeed Al-Jabr's recommendation and found it to be exceptional. My body stays moist, particularly on cold days. Dryness tends to increase, making this lotion a godsend for those with dry skin.
Prebiotic Fiber Inulin
9.5
Convenient immune support
Most Useful Review
I trust this brand's supplements completely! I've tried various products and found them to be of excellent quality at a reasonable price. I bought this for immune support during colds, and it has performed excellently. The packaging is tidy, closing securely with capsules that are easy to use.
8.8
Mild cold symptoms
Most Useful Review
My entire family takes it, and it helps keep colds and viral symptoms mild!
Melatonin
9
Melatonin mitigates banana cold injury
Comparative transcriptomic analysis reveals the reactive oxygen species metabolism involving in melatonin-alleviated chilling injury in postharvest banana fruit.
Most Relevant Research
We explored how melatonin treatment affects chilling injury in bananas during cold storage. The study revealed that bananas treated with 500 μmol L of melatonin significantly reduced the signs of chilling injury compared to untreated control fruits during 96 hours of storage.
We observed notable changes in the activity of reactive oxygen species (ROS) metabolism. The melatonin-treated bananas showed lower rates of ROS production while also displaying higher levels of beneficial compounds like ascorbic acid and glutathione. Furthermore, the treatment helped maintain the activity of key antioxidant enzymes that typically decline under cold stress.
A thorough analysis of gene expression found 1858 differentially expressed genes, indicating how melatonin influences various biological pathways in the fruit. Interestingly, melatonin seems to boost the expression of antioxidant enzyme genes while inhibiting the expression of a gene responsible for ROS production.
Overall, these findings provide valuable insights into how melatonin can effectively mitigate cold-related injuries in bananas, helping preserve their quality during storage.
We observed notable changes in the activity of reactive oxygen species (ROS) metabolism. The melatonin-treated bananas showed lower rates of ROS production while also displaying higher levels of beneficial compounds like ascorbic acid and glutathione. Furthermore, the treatment helped maintain the activity of key antioxidant enzymes that typically decline under cold stress.
A thorough analysis of gene expression found 1858 differentially expressed genes, indicating how melatonin influences various biological pathways in the fruit. Interestingly, melatonin seems to boost the expression of antioxidant enzyme genes while inhibiting the expression of a gene responsible for ROS production.
Overall, these findings provide valuable insights into how melatonin can effectively mitigate cold-related injuries in bananas, helping preserve their quality during storage.
8.8
Avoids common cold
Most Useful Review
This vitamin is a superior quality supplement that has made a noticeable difference in my life. I’ve experienced improvements in both my work performance and mood. This supplement has helped me avoid the common cold. It’s fantastic for the whole family!
Goldenseal
9.5
Prevents illness effectively
Most Useful Review
Nature's Way Goldenseal Root is remarkable - I believe it prevents me from falling ill. If I feel a cold coming on, it effectively eliminates it. This preventive remedy is essential for me; whenever I haven't taken it, or if I’ve run out, I start to feel unwell or get some kind of infection. In my view, the root proves to be more potent and effective than the herb.
9.5
Effective quality
Most Useful Review
This Goldenseal really works! It is of very high quality and performs excellently for us. I take three in the morning and three at night when I sense a cold beginning.
Alpha Lipoic Acid
7
Effectiveness of Vitamin C on Colds
Vitamin C for the common cold and pneumonia.
Most Relevant Research
We explored the effects of vitamin C on the common cold and pneumonia by examining a range of studies. Interestingly, research on animals suggests that vitamin C may have protective effects against infections. However, when it comes to preventing colds in the general population, taking more than 1 gram of vitamin C per day didn’t show significant benefits.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
9.5
No colds at all
Most Useful Review
I take this alpha lipoic acid two times a day on an empty stomach (1200mg/day). It's been two years since then, but my skin has become lustrous, my hair has regained its lively black colour, and I don't catch colds at all. The rejuvenation is significant, especially after ensuring I take all the basic nutrients. Japan is known for its additives, and I feel I need to protect my body myself since we can't rely on decent food alone. α-Lipoic acid is vital for men and women of all ages, and I believe it should be a regular purchase, even at a higher price, as it truly improves health.
Astaxanthin
9.5
Cures cold effectively
Most Useful Review
It works brilliantly! I take a 4 mg dose once a day, and my vision has improved significantly—I'm reading without glasses now. If I sense I'm catching a cold, I take an extra tablet at night and wake up feeling fresh as a cucumber.
9.5
Excellent cold remedy
Most Useful Review
Super drug! The instant I notice the first signs of a cold, I immediately observe an excellent effect. When I fall ill, it seems to shorten the duration of the illness.
Oregano Spices
9.5
Effective for cold
Most Useful Review
A great natural anti-inflammatory antibiotic; I drink it when I have a cold.
9.5
Cold remedy effective
Most Useful Review
Whenever I feel a cold coming on, I soak it to drink for two days, and the cold heals.
Chamomile Tea
9.5
Soothes throat well
Most Useful Review
This is a must-have! I boil it with every cold issue for drinking, and it works wonderfully for my throat.
9.5
Great packaging
Most Useful Review
Very useful for colds; a great product with excellent packaging and speedy delivery.
Herbal Tea
8.8
Strengthens immunity
Most Useful Review
Echinacea's most notable property is its ability to strengthen the immune system, aiding the body against pathogens. Using the plant during a cold allows utilisation of its rich composition, enhancing resistance to microorganisms, including viruses. Research indicates that regular echinacea extract intake can reduce cold instances by 55%. I consume it from September to May, brewing a litre jar with one tablespoon daily for my family. For the children, I use more drops of ChildLife Echinacea, Natural Orange flavour. Just ensure there are no allergies.
9.5
Tasty immune tea
Most Useful Review
Echinacea works wonderfully! We make immune tea at the first sign of illness or during cold season. I mix echinacea with pau d'arco, peppermint, and elderberry. The tea is delectable, aromatic, and remarkably healthy, even pleasing the children. Honey and lemon can be added if desired.
Ashwagandha
9.5
Improved sleep quality
Most Useful Review
My brother's experience: I bought two boxes, and my brother started using one. Thank God, he is sleeping well. The quality is excellent, and the quantity lasts for two months. The smell is light and acceptable. He began using it today, and I will return to update you on my experience, but I was delayed due to cleaning with thyme oil and probiotics. Yesterday, I tried my first pill when I had a cold and a runny nose. I swear I slept without feeling anything, and my nose cleared up. This is the first time I’ve slept without hearing the noise from the street. I will share the results soon. Please like if my comment helps you.
8
Viral recovery
Most Useful Review
I have been taking this supplement for a short time, but I’ve noticed a strengthening of my immune system. I caught something viral, but I recovered almost unnoticed. A slight stuffy nose and general weakness were my only noticeable symptoms, and they passed in two days! I used to have a common cold that lasted longer. I doubled my daily dose during this period and felt no residual weakness after returning to the gym. Overall, I’m pleased with the supplement's quality and ingredients.
Calcium
5
Vitamin D and cold symptoms
The Effects of Vitamin D Supplementation on Respiratory Infections in Children under 6 Years Old: A Systematic Review.
Most Relevant Research
We explored the effects of vitamin D supplementation on respiratory infections, particularly colds, in children under six years old. By examining various studies published until February 2023, we observed diverse findings, with some studies reporting benefits while others found no significant advantage. Overall, eight studies were included, with a total of 2,189 children assessed.
While a few studies indicated that low vitamin D levels might be linked to an increased risk of respiratory infections, only one study specifically noted that children who took 800 IU of vitamin D daily for three months experienced fewer mild respiratory symptoms and recovered more quickly. However, a significant number of studies showed no notable differences in the rates or severity of colds when vitamin D supplementation was used.
In essence, the evidence regarding vitamin D's role in preventing or effectively treating colds in young children is still unclear. We did find some indications that certain doses, like 80 IU/kg/day, may help reduce acute respiratory infection risks, but most research highlighted only minor benefits, such as quicker recovery rather than preventing infections. Variability in study design and supplementation protocols contributed to these inconclusive results, highlighting the need for further research.
While a few studies indicated that low vitamin D levels might be linked to an increased risk of respiratory infections, only one study specifically noted that children who took 800 IU of vitamin D daily for three months experienced fewer mild respiratory symptoms and recovered more quickly. However, a significant number of studies showed no notable differences in the rates or severity of colds when vitamin D supplementation was used.
In essence, the evidence regarding vitamin D's role in preventing or effectively treating colds in young children is still unclear. We did find some indications that certain doses, like 80 IU/kg/day, may help reduce acute respiratory infection risks, but most research highlighted only minor benefits, such as quicker recovery rather than preventing infections. Variability in study design and supplementation protocols contributed to these inconclusive results, highlighting the need for further research.
9.5
Quick results for cold
Most Useful Review
This calcium has been a game-changer for my sensitive tooth enamel. For years, I found that various toothpastes had no effect. Following local reviews, I chose this specific product, and I'm delighted with the outcome; it lessened my reaction to cold, hot, and sour foods by the third day! I've stocked up on it and feel incredibly satisfied. I've also noticed improvements in my restless legs syndrome after taking two capsules daily.
Inositol
8
Inositol transporter's role in cold
The Vacuolar Inositol Transporter BvINT1;1 Contributes to Raffinose Biosynthesis and Reactive Oxygen Species Scavenging During Cold Stress in Sugar Beet.
Most Relevant Research
We examined how inositol, a key component in the production of raffinose, plays a role in helping sugar beet plants withstand cold stress. In the study, researchers identified the vacuolar inositol transporter BvINT1;1, which seems to be critical for the synthesis of raffinose under chilly conditions.
When plants were exposed to cold, BvINT1;1 was found to be highly active, ensuring adequate inositol was available for raffinose production. Interestingly, sugar beet mutants that lacked functional BvINT1;1 not only had higher levels of inositol but also lower amounts of raffinose when subjected to cold stress.
This reduction in raffinose was significant because raffinose can help neutralize harmful reactive oxygen species (ROS), which accumulate when plants are stressed. As a result, these mutants showed increased expression of genes related to ROS, pointing out a potential risk for them during cold weather.
Overall, our findings suggest that the transporter BvINT1;1 is not just about moving inositol; it plays a vital role in boosting the plant's cold resilience by facilitating raffinose biosynthesis and maintaining balance against oxidative stress.
When plants were exposed to cold, BvINT1;1 was found to be highly active, ensuring adequate inositol was available for raffinose production. Interestingly, sugar beet mutants that lacked functional BvINT1;1 not only had higher levels of inositol but also lower amounts of raffinose when subjected to cold stress.
This reduction in raffinose was significant because raffinose can help neutralize harmful reactive oxygen species (ROS), which accumulate when plants are stressed. As a result, these mutants showed increased expression of genes related to ROS, pointing out a potential risk for them during cold weather.
Overall, our findings suggest that the transporter BvINT1;1 is not just about moving inositol; it plays a vital role in boosting the plant's cold resilience by facilitating raffinose biosynthesis and maintaining balance against oxidative stress.
9.5
Restored normal breathing
Most Useful Review
After frequent colds, my sense of smell decreased—it didn't vanish, merely dulled, with one nostril often blocked. However, my nose eventually began to breathe! I could finally perceive all the scents while walking down the street—the aroma of grass and flowers. At home, I even detected the smell of shower gel! What a joy it is to breathe normally! Thank you!!
Vitamin E
8.8
Reduced cold feeling
Most Useful Review
Excellent! I often felt sluggish and cold when not drinking. During my period, I endured a melancholic state. Since starting E, I feel less cold, and the pain from awful menstrual cramps has improved remarkably.
9.5
Better circulation noted
Most Useful Review
I've been on megavitamins for several years due to concerning health check results. I take 2000 IU daily; they're small and easy to take, and significantly improve my sensitivity to cold! My blood circulation has enhanced, leading to improved health check results. I plan to continue this for life.
D Mannose
NOW Foods D-Mannose
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 10 Reviews
8.7
8.8
Strong combo improvement
Most Useful Review
My go-to for keeping UTIs at bay in colder months! I pair it with cranberry extract for a potent combination. I notice a considerable difference with D-mannose. The capsules are larger but easy to swallow, and the dosage is just right. I'm genuinely happy with this product!
9.5
Natural remedy effective
Most Useful Review
Natural antibiotic saves during the cold season. I experienced issues with my kidneys, and this product is essential - right to mannose and cranberries. I consume plenty of water, and everything returns to normal. There are no side effects, and I was pleased to discover it.
Aconitum Napellus
9.5
Nips colds quickly
Most Useful Review
Love this one. It works wonderfully for nipping colds in the bud.
9.5
Stops colds effectively
Most Useful Review
This product stops a cold in its tracks. I always use it at the first signs of a cold; sometimes these are the only signs I experience. If the cold progresses, I simply add vitamin C and Air Power, and I'm good to go.
MSM
8.3
Improved cold resistance
Most Useful Review
Very useful for joints and more. I started taking MSM alongside collagen and vitamin C 900 mg soluble. I also tried dogrose tincture, and it really helped! My joints improved significantly – they no longer hurt and could manage heavy loads, plus I started catching fewer colds. Previously, if there was a draft or I got too cool, I would quickly come down with a cold or even herpes on my nose. I even experimented sitting by an open window in winter in shorts, and nothing happened! The capsules are convenient for those with little time who dislike the taste of MSM. Swallowing the capsules is quick and easy.
10
Cold extremities improved
Most Useful Review
This MSM is miraculous. My parents have suffered from cold hands and feet for 60 years, but it seems we’ve finally found the solution. When I took it with vitamin C, the effects were immediate and I was truly surprised. We will definitely continue using it.
Collagen Supplements
9.5
Must-have for knees
Most Useful Review
It really works! My knees no longer fear the cold. It has become an essential item for me—I've come to rely on it completely!
9.5
Effective joint support
Most Useful Review
The effect is truly remarkable! It works exceptionally well for joints. I bought it for my mother, who complained of knee pain when ascending and descending stairs. After just two weeks, she began to experience results. Besides the pain in her knees when going up and down stairs, she no longer feels discomfort like before when the weather gets colder. The packaging and price are very attractive! Highly recommended!
Beta Carotene
9
Vitamin A's key role in thermogenesis
Intact vitamin A transport is critical for cold-mediated adipose tissue browning and thermogenesis.
Most Relevant Research
We explored how vitamin A affects our body’s response to cold, specifically looking at its role in transforming white fat into brown fat, a process known as browning. This transformation is significant, as it can help reduce obesity and improve metabolic health.
In our investigation, we conducted cold exposure studies involving both mice and humans. We observed that exposure to cold led to an increase in circulating vitamin A, also known as retinol, and its transporter protein, Rbp. However, in mice lacking this protein, we found that their ability to adapt to the cold and promote thermogenesis—essentially, generating heat through fat—was severely compromised.
Interestingly, we also noted that stimulating human fat cells with retinol heightened the expression of genes associated with thermogenesis and boosted mitochondrial activity, which is vital for burning fat. In humans, the rise in vitamin A during cold exposure hinted at improved fat utilization.
Overall, our findings revealed that not only are vitamin A levels responsive to cold, but effective transportation of this vitamin is crucial for cold-induced fat browning and the body's ability to generate heat.
In our investigation, we conducted cold exposure studies involving both mice and humans. We observed that exposure to cold led to an increase in circulating vitamin A, also known as retinol, and its transporter protein, Rbp. However, in mice lacking this protein, we found that their ability to adapt to the cold and promote thermogenesis—essentially, generating heat through fat—was severely compromised.
Interestingly, we also noted that stimulating human fat cells with retinol heightened the expression of genes associated with thermogenesis and boosted mitochondrial activity, which is vital for burning fat. In humans, the rise in vitamin A during cold exposure hinted at improved fat utilization.
Overall, our findings revealed that not only are vitamin A levels responsive to cold, but effective transportation of this vitamin is crucial for cold-induced fat browning and the body's ability to generate heat.
9.5
Quick recovery noted
Most Useful Review
Fine! I truly appreciated this natural beta carotene. I took it myself and also gave it to my husband at the first signs of a cold, and his recovery was rapid! The benefits are evident. The capsules are small, soft, and easy to swallow, and the packaging is convenient, taking up little space in the refrigerator. NOW Foods products consistently demonstrate high quality.
Slippery Elm
9.5
Calms the stomach
Most Useful Review
Smooth elm bark is beneficial for dropsy, chronic rheumatism, and fever as an anti-cold remedy, and externally acts as an anti-inflammatory for burns.
8.8
Effective comfort during colds
Most Useful Review
This product has become a valuable addition to our natural remedy kit. With 100 small, easy-to-swallow capsules, the 400 mg dosage allows for appropriate intake without increasing the daily amount. During the cold season, it effectively soothes throat irritation and provides comfort to the stomach. Unlike syrups or powders, these capsules are portable and convenient, with no aftertaste. The composition is entirely natural, instilling confidence in its quality. Regular usage significantly aids with mucous membrane irritation and stomach discomfort, strengthening the body over time. The size and natural ingredients make it an exceptional option for anyone seeking a gentle remedy.
Mineral Bath
9.5
Effective for muscle aches
Most Useful Review
I generally use a smaller amount than recommended, yet I can still feel the impact. If you're experiencing muscle aches or feel cold, it's advisable to add more. It's excellent that it doesn't get cold after leaving the bath.
9.5
No cold sensation
Most Useful Review
It gets very warm! Normally, I feel cold after a bath, but not this time! I’m unsure if it works because it's odourless, but I think it does. I'll definitely repeat it when this runs out.
Zinc
8
Zinc mouthwash reduces cold symptoms
Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms.
Most Relevant Research
We explored the impact of regular gargling with an antimicrobial mouthwash that contains both cetylpyridinium chloride and zinc on upper respiratory symptoms. A total of 150 participants were split into two groups; one group just brushed their teeth, while the other group brushed and gargled with the mouthwash twice a day over three months.
Our findings revealed that those using the mouthwash experienced a 21.5% reduction in the frequency and an 11% decrease in the severity of respiratory symptoms. This strongly suggests that incorporating zinc, alongside cetylpyridinium chloride, can provide benefits for those suffering from cold-related symptoms.
However, it’s important to note that this study’s design involved multiple components, and we can’t isolate zinc’s effectiveness from the impact of the other ingredients. Still, the results encourage us to view mouthwash with these ingredients as a helpful addition to our daily hygiene routines, especially during cold and flu season.
Ultimately, this research indicates that gargling with a mouthwash containing zinc and cetylpyridinium chloride can indeed help alleviate some unpleasant cold symptoms, but we should be mindful of the combination's effects when interpreting these outcomes.
Our findings revealed that those using the mouthwash experienced a 21.5% reduction in the frequency and an 11% decrease in the severity of respiratory symptoms. This strongly suggests that incorporating zinc, alongside cetylpyridinium chloride, can provide benefits for those suffering from cold-related symptoms.
However, it’s important to note that this study’s design involved multiple components, and we can’t isolate zinc’s effectiveness from the impact of the other ingredients. Still, the results encourage us to view mouthwash with these ingredients as a helpful addition to our daily hygiene routines, especially during cold and flu season.
Ultimately, this research indicates that gargling with a mouthwash containing zinc and cetylpyridinium chloride can indeed help alleviate some unpleasant cold symptoms, but we should be mindful of the combination's effects when interpreting these outcomes.
9.5
Works instantly
Most Useful Review
This zinc is the best form, acting immediately at the first sign of a cold. I take one tablet combined with 1000mg of vitamin C, and I feel perfectly well by morning. It's indispensable during winter. I struggled to find this particular form of zinc as it sells out rapidly. Thank you for keeping me healthy!
Childrens Sleep Aids
9
Melatonin mitigates banana cold injury
Comparative transcriptomic analysis reveals the reactive oxygen species metabolism involving in melatonin-alleviated chilling injury in postharvest banana fruit.
Most Relevant Research
We explored how melatonin treatment affects chilling injury in bananas during cold storage. The study revealed that bananas treated with 500 μmol L of melatonin significantly reduced the signs of chilling injury compared to untreated control fruits during 96 hours of storage.
We observed notable changes in the activity of reactive oxygen species (ROS) metabolism. The melatonin-treated bananas showed lower rates of ROS production while also displaying higher levels of beneficial compounds like ascorbic acid and glutathione. Furthermore, the treatment helped maintain the activity of key antioxidant enzymes that typically decline under cold stress.
A thorough analysis of gene expression found 1858 differentially expressed genes, indicating how melatonin influences various biological pathways in the fruit. Interestingly, melatonin seems to boost the expression of antioxidant enzyme genes while inhibiting the expression of a gene responsible for ROS production.
Overall, these findings provide valuable insights into how melatonin can effectively mitigate cold-related injuries in bananas, helping preserve their quality during storage.
We observed notable changes in the activity of reactive oxygen species (ROS) metabolism. The melatonin-treated bananas showed lower rates of ROS production while also displaying higher levels of beneficial compounds like ascorbic acid and glutathione. Furthermore, the treatment helped maintain the activity of key antioxidant enzymes that typically decline under cold stress.
A thorough analysis of gene expression found 1858 differentially expressed genes, indicating how melatonin influences various biological pathways in the fruit. Interestingly, melatonin seems to boost the expression of antioxidant enzyme genes while inhibiting the expression of a gene responsible for ROS production.
Overall, these findings provide valuable insights into how melatonin can effectively mitigate cold-related injuries in bananas, helping preserve their quality during storage.
9
Easy sleep for kids
Most Useful Review
My 5.5-year-old takes this in autumn and winter when it's cold and dark early. It helps him fall asleep easily within 15 minutes, preventing him from lying awake for hours. He wakes up well-rested.
Lactoferrin
9
Evaluating lactoferrin for colds
Supporting respiratory epithelia and lowering inflammation to effectively treat common cold symptoms: A randomized controlled trial.
Most Relevant Research
We conducted a study to investigate the potential of a throat spray containing lactoferrin, along with other ingredients, to alleviate cold symptoms. This double-blind, placebo-controlled trial involved 157 participants who self-administered treatments and reported their experiences over 36 hours. We aimed to see if this combination could improve upon the effectiveness of aspirin, which has shown only modest benefits in relieving cold symptoms.
While our findings indicated that the treatment significantly reduced sore throat pain and other cold symptoms, it is important to note that the exact contribution of lactoferrin remains unclear. This is because the throat spray included multiple active components, including lysozyme and aloe, making it difficult to isolate lactoferrin's specific effects. Overall, we observed a marked reduction in symptom severity, with improvements noted across the board for the treatments administered.
Although this study highlighted a promising approach to supporting respiratory health and managing cold symptoms, we cannot definitively say that lactoferrin alone was responsible for these outcomes. Thus, while the results are encouraging, additional research is needed to clarify the distinct role of lactoferrin in treating colds.
While our findings indicated that the treatment significantly reduced sore throat pain and other cold symptoms, it is important to note that the exact contribution of lactoferrin remains unclear. This is because the throat spray included multiple active components, including lysozyme and aloe, making it difficult to isolate lactoferrin's specific effects. Overall, we observed a marked reduction in symptom severity, with improvements noted across the board for the treatments administered.
Although this study highlighted a promising approach to supporting respiratory health and managing cold symptoms, we cannot definitively say that lactoferrin alone was responsible for these outcomes. Thus, while the results are encouraging, additional research is needed to clarify the distinct role of lactoferrin in treating colds.
9.5
Reduced colds effect
Most Useful Review
Lactoferrin, 250 mg, was suggested by my primary care physician due to my frequent colds, as I work in a Public High School. It has made a significant difference! I plan to take it regularly from now on.
Quercetin
8
Quercetin limits HRV1B replication
Quercetin-3-Methyl Ether Induces Early Apoptosis to Overcome HRV1B Immune Evasion, Suppress Viral Replication, and Mitigate Inflammatory Pathogenesis.
Most Relevant Research
We investigated how quercetin-3-methyl ether, a natural flavonoid, impacts human rhinovirus 1B (HRV1B), which is responsible for the common cold and can worsen conditions like asthma. Our research involved testing this compound in HeLa cells to see if it could reduce viral replication and the damage associated with the virus.
In our experiments, quercetin-3-methyl ether significantly inhibited the replication of HRV1B in a concentration-dependent way, which means that higher doses produced better results. We also found that this compound enhanced early apoptosis—essentially, the process by which infected cells shut down in response to the virus—during the critical early stages of infection. This seemed to counteract HRV1B's tactics to evade the immune response.
Additionally, when we administered quercetin-3-methyl ether to mice infected with HRV1B, we observed a noteworthy reduction in viral RNA levels and inflammation in their lung tissues, suggesting a potential therapeutic effect. Our findings enhance the understanding of quercetin-3-methyl ether as a novel agent against HRV1B, pointing towards promising strategies for managing cold-related illnesses and their complications.
In our experiments, quercetin-3-methyl ether significantly inhibited the replication of HRV1B in a concentration-dependent way, which means that higher doses produced better results. We also found that this compound enhanced early apoptosis—essentially, the process by which infected cells shut down in response to the virus—during the critical early stages of infection. This seemed to counteract HRV1B's tactics to evade the immune response.
Additionally, when we administered quercetin-3-methyl ether to mice infected with HRV1B, we observed a noteworthy reduction in viral RNA levels and inflammation in their lung tissues, suggesting a potential therapeutic effect. Our findings enhance the understanding of quercetin-3-methyl ether as a novel agent against HRV1B, pointing towards promising strategies for managing cold-related illnesses and their complications.
9.5
Improves colds effect
Most Useful Review
Quercetin is associated with enhanced exercise performance and reduced inflammation, blood pressure, and blood sugar levels. The typical dose is 500 mg daily. This supplement contains 29 mg of Bio-Quercetin phytosome, equating to 10 mg of quercetin but claims 50 times greater bioavailability. I used it for a cold, and it worked brilliantly. Additionally, I understand it's part of the anti-COVID protocol, so I keep it at home during these challenging times. Stay healthy!
Echinacea Goldenseal
9.5
Effective for children
Most Useful Review
I have been using this on my 6-year-old, and it stopped the cold in its tracks. I am also using it on my 2.5-year-old, and it seems to work well too. I mix it with water for my older child and with juice for my younger one; they both take it without any problems.
8.8
Prevents cold onset
Most Useful Review
Great stuff! I adore this product. I utilise it at the first sign of a cold and often manage to keep the cold from developing.
Coconut Oil
9.5
Improves circulation issues
Most Useful Review
I am very pleased with my order from this company. I used coconut oil about a year ago after discovering it helps with circulation issues. I have Raynaud's disease, where my fingers turn white and go numb from the cold. After using this product daily for less than two weeks, I hardly experience circulation problems anymore. I've also lost weight using this product every day.
9.5
Highly recommend
Most Useful Review
I absolutely love this coconut oil! The delightful scent from cold pressing makes it perfect for pancakes, cheesecakes, and cereals. Our family needs this for 3-4 months, and the quality is outstanding. I'm extremely satisfied and would certainly recommend it!
Face Wash Cleansers
9.5
Effective cold cream
Most Useful Review
An excellent cream for the cold season.
9.5
Moisturises in cold
Most Useful Review
This product is ideal for combined to oily, sensitive, and acne-prone skin, being free from harmful ingredients. Initially, I had reservations, but it has proven to be of excellent quality. I follow the recommended usage frequency on the packaging. The clean ingredients make it suitable for all ages. I've noticed benefits after just one day's use; it has a smooth texture that moisturises straight away, particularly during the cold and dry season, with a pleasantly mild scent. Gentle cleansing even works for mascara.
Dong Quai Angelica
8.8
Cold-free winter
Most Useful Review
This is effective for improving poor circulation! Many Chinese herbs can be pricey, so I'm pleased to buy Angelica acutiloba at this cost. Two months in, I noticed it effectively improved my circulation. This winter, I wasn't concerned about feeling colder than usual. I intend to keep taking it each winter.
8.8
Warming menopause relief
Most Useful Review
I purchased this to assist with my sensitivity to cold. I feel my body gradually warming from within, aiding my experience with menopause. I previously used Inochi no Haha but have concluded that supplements are preferable to medication.
Childrens Vitamin D
8
Vitamin D enhances cold resilience
Influence of Vitamin D Supplementation by Simulated Sunlight or Oral D3 on Respiratory Infection during Military Training.
Most Relevant Research
We delved into the effects of vitamin D on cold symptoms among military recruits during their training. In two comprehensive studies, we observed over 1,600 military recruits to see how their vitamin D levels impacted their likelihood of upper respiratory tract infections (URTIs) throughout the seasons.
In the first study, only 21% of recruits were found to have sufficient vitamin D levels during winter. Notably, those with adequate vitamin D were 40% less likely to experience URTIs compared to those who were deficient. Each URTI typically caused three missed training days, indicating a significant impact on their training schedules.
Following this, we conducted a randomized controlled trial with 250 men simulating sunlight exposure or providing oral vitamin D3 supplementation. Our goal was to see how both methods affected overall vitamin D levels and, subsequently, URTI symptoms. Remarkably, both strategies successfully brought participants to sufficient vitamin D levels. Compared to those who received a placebo, those getting vitamin D3 experienced a 15% reduction in the severity of cold symptoms and a 36% decrease in the number of days with URTI.
Interestingly, we found that both methods—simulated sunlight and oral supplementation—were equally effective, and neither had a significant impact on specific immune response markers.
In the first study, only 21% of recruits were found to have sufficient vitamin D levels during winter. Notably, those with adequate vitamin D were 40% less likely to experience URTIs compared to those who were deficient. Each URTI typically caused three missed training days, indicating a significant impact on their training schedules.
Following this, we conducted a randomized controlled trial with 250 men simulating sunlight exposure or providing oral vitamin D3 supplementation. Our goal was to see how both methods affected overall vitamin D levels and, subsequently, URTI symptoms. Remarkably, both strategies successfully brought participants to sufficient vitamin D levels. Compared to those who received a placebo, those getting vitamin D3 experienced a 15% reduction in the severity of cold symptoms and a 36% decrease in the number of days with URTI.
Interestingly, we found that both methods—simulated sunlight and oral supplementation—were equally effective, and neither had a significant impact on specific immune response markers.
9.5
Excellent vitamins
Most Useful Review
Received vitamins promptly, excellent remedies for colds. I give my child two per day; I thoroughly appreciate them. I believe "Garden of Life" products are the best for my children! 👍👍👍
Peppermint Oil
9.5
Very effective cooling oil
Most Useful Review
This peppermint oil is delightful, particularly in clay masks, where it provides a refreshing "bite." It's a good quality oil!
9.5
Calms and disinfects
Most Useful Review
I purchased peppermint essential oil in a 30 ml dark brown glass bottle with a drop dispenser. Its delicate, fresh aroma is invigorating, and it calms and reduces stress while providing a cold sensation. It has an antispasmodic effect on brain vessels, destroys viruses and disinfects the air, making it a common ingredient in cold medications. I love adding a few drops to the diffuser.
Arsenicum Album
9.5
Helps with colds
Most Useful Review
Great. It aids with colds accompanied by thick yellow nasal discharge.* Based on the practice of natural remedies rather than traditional evidence-based medicine, this drug has not been evaluated by the FDA (US Food and Drug Administration).
8.8
Effective for cold
Most Useful Review
I always keep it on hand as my remedy for food poisoning. Being sensitive to the cold, it proved effective when I took it at night amid anxiety, making it difficult to sleep. Although the packaging I received was messy compared to when I bought it in Japan, it didn’t affect its use.
Ginkgo Biloba
9.5
Relieved roughness
Most Useful Review
I no longer get rough skin. I suggested this supplement to my mother due to its various benefits. While there wasn't a dramatic change in its claimed efficacy, he mentioned that his rough hands, which used to crack in the cold, have improved since he started taking it.
9.5
Cold feet gone
Most Useful Review
Ginkgo Biloba is my go-to. I regularly take 60 mg daily in three-month courses, sometimes increasing to 120 mg. I've noticed enhanced brain activity, particularly with simultaneous tasks, and my cold feet issue has vanished. Previously, I wore woollen socks year-round, but after several courses of ginkgo, the problem disappeared. I have hypotension, and ginkgo does not affect my blood pressure negatively. This supplement is simply magical for me.
Castor
9.5
Good for early signs
Most Useful Review
I take it regularly at the first sign of a cold, and it works well for me. Unlike pharmacy oils, it has no unpleasant smell.
8.8
Protects against viruses
Most Useful Review
Helpful! I bought this at a great price for lymphatic system treatment using castor packets. I'm pleased with the oil's quality and effect. During cold spells, I apply it to the nasal mucosa, which keeps it moist and shields it from viruses.
Broccoli
8.8
Immune improvement
Most Useful Review
Resistance enhancement! I have found it difficult to catch a cold now since my immune ability has increased from taking this consistently every day.
9.5
Prevents cold easily
Most Useful Review
Sulforaphane is essential in my supplements, as it seems to make it not easy for me to catch a cold.
Pomegranate Oil
8.8
Reduces wrinkles
Most Useful Review
Oh, that's splendid! This is genuinely cold-pressed oil. The quality is exceptional, with a delicate aroma of pomegranate and a lovely pink colour. I apply it to areas with wrinkles after using rose water. After a short wait, I then apply serum and cream. The oil has a thick consistency, but absorbs well into the skin. I am very pleased with the results; with regular use, wrinkles have diminished and my skin looks improved. As I also make handmade creams, pomegranate oil will be included in my formulations. Without a doubt, I will continue to purchase! The convenient packaging features a dropper, making it ideal for dry skin and anti-aging care.
8.8
Highly moisturising
Most Useful Review
Cold pressed, highly moisturising, recommended for mature skin, very good.
Cacao
9.5
Pain relief for throat
Most Useful Review
I wish there was an option for 10 stars for this product. It’s an amazing cocoa—delicious and beneficial. I give it to my children during colds, as it really softens throat pain. Highly recommended!
8.8
Invigorating in winter
Most Useful Review
I adore this drink, especially in the cold season! It invigorates, restores strength, and warms me up. We enjoy it without sugar, adding pepper and cinnamon. I will order more!
Childrens Calcium
9.5
Prevents cold
Most Useful Review
These tasty gummies are genuinely effective. My husband and I each take two a day, and we have not had a cold or flu throughout the fall or winter season.
8.8
Reduced cold frequency
Most Useful Review
After a long search for a quality vitamin composition for my children, I bought these. They drink them happily - the taste is natural, without any chemical aftertastes. I’ve noticed that since they started taking them, my children have had more energy. Their appetite and immunity have improved, leading to fewer colds, and when colds do occur, they pass more easily. The composition is exceptional, without unnecessary additives. I recommend it to all caring parents!
Rutin
9.5
Speeds cold recovery
Most Useful Review
Be sure to take rutin when you have a cold; it aids in removing toxins and viruses from the blood more quickly, leading to faster recovery. It should ideally be consumed alongside vitamin C.
9
Strengthened immune system
Most Useful Review
I have been taking this supplement for a short while and have already noticed an improvement in my immune system. When I caught a common virus in 2020, I recovered nearly unnoticed; I experienced only a slight stuffy nose and weakness for two days, which is much quicker than my usual colds. I doubled my usual dosage during this time, and noticed no residual weakness afterward. I'm pleased with the supplement's quality and ingredients.
Ester C
7
Effectiveness of Vitamin C on Colds
Vitamin C for the common cold and pneumonia.
Most Relevant Research
We explored the effects of vitamin C on the common cold and pneumonia by examining a range of studies. Interestingly, research on animals suggests that vitamin C may have protective effects against infections. However, when it comes to preventing colds in the general population, taking more than 1 gram of vitamin C per day didn’t show significant benefits.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
9.5
Effective cold remedy
Most Useful Review
A super remedy for colds and Covid. I keep it in my first aid kit for everyone. In the initial days of a cold, I take 1 tablet three times a day for 3-5 days, then reduce the dose to 1 tablet daily for up to 14 days. It helped me cope with the illness.
Ip6
8
Inositol transporter's role in cold
The Vacuolar Inositol Transporter BvINT1;1 Contributes to Raffinose Biosynthesis and Reactive Oxygen Species Scavenging During Cold Stress in Sugar Beet.
Most Relevant Research
We examined how inositol, a key component in the production of raffinose, plays a role in helping sugar beet plants withstand cold stress. In the study, researchers identified the vacuolar inositol transporter BvINT1;1, which seems to be critical for the synthesis of raffinose under chilly conditions.
When plants were exposed to cold, BvINT1;1 was found to be highly active, ensuring adequate inositol was available for raffinose production. Interestingly, sugar beet mutants that lacked functional BvINT1;1 not only had higher levels of inositol but also lower amounts of raffinose when subjected to cold stress.
This reduction in raffinose was significant because raffinose can help neutralize harmful reactive oxygen species (ROS), which accumulate when plants are stressed. As a result, these mutants showed increased expression of genes related to ROS, pointing out a potential risk for them during cold weather.
Overall, our findings suggest that the transporter BvINT1;1 is not just about moving inositol; it plays a vital role in boosting the plant's cold resilience by facilitating raffinose biosynthesis and maintaining balance against oxidative stress.
When plants were exposed to cold, BvINT1;1 was found to be highly active, ensuring adequate inositol was available for raffinose production. Interestingly, sugar beet mutants that lacked functional BvINT1;1 not only had higher levels of inositol but also lower amounts of raffinose when subjected to cold stress.
This reduction in raffinose was significant because raffinose can help neutralize harmful reactive oxygen species (ROS), which accumulate when plants are stressed. As a result, these mutants showed increased expression of genes related to ROS, pointing out a potential risk for them during cold weather.
Overall, our findings suggest that the transporter BvINT1;1 is not just about moving inositol; it plays a vital role in boosting the plant's cold resilience by facilitating raffinose biosynthesis and maintaining balance against oxidative stress.
9.5
Fast recovery
Most Useful Review
Excellent! I really, really like this drug. I take it consistently for myself and my friend. It perfectly alleviates cold symptoms, leading to much faster recovery. There’s no drowsiness or any other unpleasant side effects. It boosts my immunity effectively. At the first signs of a cold, I take an increased dose, then return to the usual dosage the following day. Here's to good health!
Vitamin C
7
Effectiveness of Vitamin C on Colds
Vitamin C for the common cold and pneumonia.
Most Relevant Research
We explored the effects of vitamin C on the common cold and pneumonia by examining a range of studies. Interestingly, research on animals suggests that vitamin C may have protective effects against infections. However, when it comes to preventing colds in the general population, taking more than 1 gram of vitamin C per day didn’t show significant benefits.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
8.8
Helps with cold
Most Useful Review
The quality is excellent. The best antioxidant, it supports immunity. For colds, it works effectively with zinc for a quick recovery.
Aloe Vera Skin Care
8.8
Relieves pain instantly
Most Useful Review
Useful magic for hair and skin. There is no smell, and I prefer to use it for my curly hair instead of regular hair gel. My mother suffered from severe burns, and I applied it immediately after the burn; the effect lasted for three days and relieved her pain. I also use it as a daily moisturiser for my oily skin, and it provides sweet hydration with quick absorption. I keep it in the refrigerator for a cold application.
9.5
Multi-purpose relief
Most Useful Review
Excellent product; I used it on my face, hair, and skin. It is also suitable for consumption. When applied cold, it alleviates burns or skin irritations, calming them down effectively.
Childrens Probiotics
5
Vitamin D and cold symptoms
The Effects of Vitamin D Supplementation on Respiratory Infections in Children under 6 Years Old: A Systematic Review.
Most Relevant Research
We explored the effects of vitamin D supplementation on respiratory infections, particularly colds, in children under six years old. By examining various studies published until February 2023, we observed diverse findings, with some studies reporting benefits while others found no significant advantage. Overall, eight studies were included, with a total of 2,189 children assessed.
While a few studies indicated that low vitamin D levels might be linked to an increased risk of respiratory infections, only one study specifically noted that children who took 800 IU of vitamin D daily for three months experienced fewer mild respiratory symptoms and recovered more quickly. However, a significant number of studies showed no notable differences in the rates or severity of colds when vitamin D supplementation was used.
In essence, the evidence regarding vitamin D's role in preventing or effectively treating colds in young children is still unclear. We did find some indications that certain doses, like 80 IU/kg/day, may help reduce acute respiratory infection risks, but most research highlighted only minor benefits, such as quicker recovery rather than preventing infections. Variability in study design and supplementation protocols contributed to these inconclusive results, highlighting the need for further research.
While a few studies indicated that low vitamin D levels might be linked to an increased risk of respiratory infections, only one study specifically noted that children who took 800 IU of vitamin D daily for three months experienced fewer mild respiratory symptoms and recovered more quickly. However, a significant number of studies showed no notable differences in the rates or severity of colds when vitamin D supplementation was used.
In essence, the evidence regarding vitamin D's role in preventing or effectively treating colds in young children is still unclear. We did find some indications that certain doses, like 80 IU/kg/day, may help reduce acute respiratory infection risks, but most research highlighted only minor benefits, such as quicker recovery rather than preventing infections. Variability in study design and supplementation protocols contributed to these inconclusive results, highlighting the need for further research.
9.5
Boosts immunity
Most Useful Review
An excellent tool for immunity. I began giving it to my child from birth, and now at 2 years old, I continue. This jar lasts for 1.5 months with daily doses. It seems to have made my child more resistant to colds, as he is often the last in his group to fall ill.
Ascorbic Acid
7
Effectiveness of Vitamin C on Colds
Vitamin C for the common cold and pneumonia.
Most Relevant Research
We explored the effects of vitamin C on the common cold and pneumonia by examining a range of studies. Interestingly, research on animals suggests that vitamin C may have protective effects against infections. However, when it comes to preventing colds in the general population, taking more than 1 gram of vitamin C per day didn’t show significant benefits.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
9.5
Quick recovery noted
Most Useful Review
Vitamin C in crystals is a godsend during cold season. I dilute it with raspberry juice and sugar for my children and drink it myself. It tastes lovely! With vitamins D, K-2, and zinc, I now recover in just 3-4 days, compared to the previous 7-10 days. The Vitamin C powder lasts a long time.
Feminine Hygiene
8.8
Cold sensation relief
Most Useful Review
Very impressive! This product is effective against Candida. The environmentally-friendly packaging, importantly, keeps each piece hygienic. Upon use, it feels quite cold, and I’ve obtained significant improvement. I recommend that if you are using various suppositories, use this one first to disinfect and sterilise.
9.5
Effective for vaginitis
Most Useful Review
This product shows amazing results when women feel the onset of vaginitis related to a cold. Relief typically follows overnight use, and being infused with tea tree oil allows for safe usage. Ensure to store it in the refrigerator as it can deteriorate with a slight rise in temperature. I strongly encourage women to give it a try.
Gelatin
21st Century Gelatin
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.5
9.5
Highly effective treatment
Most Useful Review
The quality is simply exceptional! It has a powerful effect on the cartilage. My wrist was in pain due to a cold affecting it, and I struggled to move it. After a doctor's visit, it turned out I might need surgery for carpal tunnel syndrome. I remembered the pills I had purchased and took two before bedtime. Remarkably, by the second day, I noticed significant improvement! It benefits my joints, including my knees, hands, and elbows. A lack of collagen contributes to joint pain, and this gelatin is a miracle worker! I'm definitely repurchasing and highly recommend it.
8.8
Knee pain relief
Most Useful Review
As a vegan, I avoid cold cuts and broths, but I run frequently. My knees sometimes feel sore, yet after taking gelatin, I've experienced relief. I have been drinking it for six months now and appreciate its effects.
Lutein
8.8
Effective for dryness
Most Useful Review
I have dry eye syndrome that feels like sand in my eyes and causes tears when exposed to cold air. I've been taking it and it appears to be effective.
8.3
Helps cold eyes
Most Useful Review
Good for dry eyes. Effective for cold and dry eyes.
Cod Liver Oil
9
Vitamin A's key role in thermogenesis
Intact vitamin A transport is critical for cold-mediated adipose tissue browning and thermogenesis.
Most Relevant Research
We explored how vitamin A affects our body’s response to cold, specifically looking at its role in transforming white fat into brown fat, a process known as browning. This transformation is significant, as it can help reduce obesity and improve metabolic health.
In our investigation, we conducted cold exposure studies involving both mice and humans. We observed that exposure to cold led to an increase in circulating vitamin A, also known as retinol, and its transporter protein, Rbp. However, in mice lacking this protein, we found that their ability to adapt to the cold and promote thermogenesis—essentially, generating heat through fat—was severely compromised.
Interestingly, we also noted that stimulating human fat cells with retinol heightened the expression of genes associated with thermogenesis and boosted mitochondrial activity, which is vital for burning fat. In humans, the rise in vitamin A during cold exposure hinted at improved fat utilization.
Overall, our findings revealed that not only are vitamin A levels responsive to cold, but effective transportation of this vitamin is crucial for cold-induced fat browning and the body's ability to generate heat.
In our investigation, we conducted cold exposure studies involving both mice and humans. We observed that exposure to cold led to an increase in circulating vitamin A, also known as retinol, and its transporter protein, Rbp. However, in mice lacking this protein, we found that their ability to adapt to the cold and promote thermogenesis—essentially, generating heat through fat—was severely compromised.
Interestingly, we also noted that stimulating human fat cells with retinol heightened the expression of genes associated with thermogenesis and boosted mitochondrial activity, which is vital for burning fat. In humans, the rise in vitamin A during cold exposure hinted at improved fat utilization.
Overall, our findings revealed that not only are vitamin A levels responsive to cold, but effective transportation of this vitamin is crucial for cold-induced fat browning and the body's ability to generate heat.
9.5
Stopped catching colds
Most Useful Review
I drink these vitamins regularly, and they have raised my immunity. Since I started taking them, I have not had a cold.
Grapeseed
NOW Foods Solutions
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 28 Reviews
8.5
9.5
Calmed my skin
Most Useful Review
This oil has been a game changer for my oily skin and large pores. In just five days, I've seen a major difference. Not only does it calm my sebum production and dry patches from the cold weather, but it also improves the tone and texture of my skin! After applying it post-cleansing, I let it sit for hours, and now my face glows. Importantly, it does not cause breakouts and has significantly reduced my oiliness.
7.5
Effective for dryness
Most Useful Review
This oil is a fantastic source of vitamin E that many people lack. It effectively calms my sebum production and dry patches from cold weather while improving my skin's tone and texture. I have before and after photos from just two days, showing a major difference! The bottle is large enough to last at least two years. After washing my face with a gentle cleanser like baby wash, I apply a thin layer for five hours and wash it off before bedtime. My face now has a lovely glow, and this oil does NOT cause breakouts! This moisturiser also closes my pores, making me less oily than before!
B3 Niacin
8
Inositol transporter's role in cold
The Vacuolar Inositol Transporter BvINT1;1 Contributes to Raffinose Biosynthesis and Reactive Oxygen Species Scavenging During Cold Stress in Sugar Beet.
Most Relevant Research
We examined how inositol, a key component in the production of raffinose, plays a role in helping sugar beet plants withstand cold stress. In the study, researchers identified the vacuolar inositol transporter BvINT1;1, which seems to be critical for the synthesis of raffinose under chilly conditions.
When plants were exposed to cold, BvINT1;1 was found to be highly active, ensuring adequate inositol was available for raffinose production. Interestingly, sugar beet mutants that lacked functional BvINT1;1 not only had higher levels of inositol but also lower amounts of raffinose when subjected to cold stress.
This reduction in raffinose was significant because raffinose can help neutralize harmful reactive oxygen species (ROS), which accumulate when plants are stressed. As a result, these mutants showed increased expression of genes related to ROS, pointing out a potential risk for them during cold weather.
Overall, our findings suggest that the transporter BvINT1;1 is not just about moving inositol; it plays a vital role in boosting the plant's cold resilience by facilitating raffinose biosynthesis and maintaining balance against oxidative stress.
When plants were exposed to cold, BvINT1;1 was found to be highly active, ensuring adequate inositol was available for raffinose production. Interestingly, sugar beet mutants that lacked functional BvINT1;1 not only had higher levels of inositol but also lower amounts of raffinose when subjected to cold stress.
This reduction in raffinose was significant because raffinose can help neutralize harmful reactive oxygen species (ROS), which accumulate when plants are stressed. As a result, these mutants showed increased expression of genes related to ROS, pointing out a potential risk for them during cold weather.
Overall, our findings suggest that the transporter BvINT1;1 is not just about moving inositol; it plays a vital role in boosting the plant's cold resilience by facilitating raffinose biosynthesis and maintaining balance against oxidative stress.
10
Cold healed
Most Useful Review
Since the flush is minimal and removing the capsule isn't painful, I give it to my child. Although it can be hard to dissolve, it seems easy to drink. I've noticed my child's cold has healed since starting this.
Acetyl L Carnitine
9.5
Reduced cold susceptibility
Most Useful Review
Absolutely brilliant! It comes in a convenient size, has no taste, and can be taken daily. Since I started using it, I’ve felt well, less susceptible to colds, and think it’s very effective.
8.8
Enhanced recovery post-cold
Most Useful Review
Carnitine is essential not only for sports but also during recovery after a cold. I began taking carnitine after suffering from a coronavirus infection when I felt weak. After 1.5 months of 500 units daily, I regained my previous energy and felt revitalised!
Xylitol
9.5
Allergy relief
Most Useful Review
Adding this to nasal washes is fantastic; it’s antibacterial and greatly aids during allergies or colds. A true helper!
8
Safe sweetener
Most Useful Review
I adore using xylitol as a sugar substitute. However, it can be somewhat hard to dissolve in cold drinks. I appreciate that it doesn’t raise blood sugar levels and serves as a natural bacteria preventative. I have had successful results baking with it and was delighted to find this brand in a larger quantity.
L Theanine
8
Inositol transporter's role in cold
The Vacuolar Inositol Transporter BvINT1;1 Contributes to Raffinose Biosynthesis and Reactive Oxygen Species Scavenging During Cold Stress in Sugar Beet.
Most Relevant Research
We examined how inositol, a key component in the production of raffinose, plays a role in helping sugar beet plants withstand cold stress. In the study, researchers identified the vacuolar inositol transporter BvINT1;1, which seems to be critical for the synthesis of raffinose under chilly conditions.
When plants were exposed to cold, BvINT1;1 was found to be highly active, ensuring adequate inositol was available for raffinose production. Interestingly, sugar beet mutants that lacked functional BvINT1;1 not only had higher levels of inositol but also lower amounts of raffinose when subjected to cold stress.
This reduction in raffinose was significant because raffinose can help neutralize harmful reactive oxygen species (ROS), which accumulate when plants are stressed. As a result, these mutants showed increased expression of genes related to ROS, pointing out a potential risk for them during cold weather.
Overall, our findings suggest that the transporter BvINT1;1 is not just about moving inositol; it plays a vital role in boosting the plant's cold resilience by facilitating raffinose biosynthesis and maintaining balance against oxidative stress.
When plants were exposed to cold, BvINT1;1 was found to be highly active, ensuring adequate inositol was available for raffinose production. Interestingly, sugar beet mutants that lacked functional BvINT1;1 not only had higher levels of inositol but also lower amounts of raffinose when subjected to cold stress.
This reduction in raffinose was significant because raffinose can help neutralize harmful reactive oxygen species (ROS), which accumulate when plants are stressed. As a result, these mutants showed increased expression of genes related to ROS, pointing out a potential risk for them during cold weather.
Overall, our findings suggest that the transporter BvINT1;1 is not just about moving inositol; it plays a vital role in boosting the plant's cold resilience by facilitating raffinose biosynthesis and maintaining balance against oxidative stress.
9.5
Helps feel better
Most Useful Review
Great product! Fast shipping, gets the job done and is super effective, helping me feel better when I'm cold. It's easy on the stomach and the good size means it doesn't taste like anything. The potency and quality of this supplement are excellent, with a good mg dosage. The packaging is perfect and descriptive, with no acidity, and I feel my immune system is up!
L Glycine
9.5
Recommended during colds
Most Useful Review
I purchased it for my mother, and everything is fine. I also give it to my children and take it myself during colds. I recommend it to others for similar use.
8.8
Improved immunity
Most Useful Review
I have always struggled with weak immunity and frequent colds. Since taking these vitamins, my life has changed dramatically. I've noticed that my body is now more resilient to infections, my energy levels have increased, and my overall well-being has significantly improved. I am grateful to the manufacturers for this fantastic product!
Stevia
8.8
Relieves cold crises
Most Useful Review
Great product! I've been using it for months to relieve crises, especially during flights. I appreciate that it easily dissolves in cold juices, unlike powdered stevia that only works in hot water. I've also made sugar-free chocolate bars with it, and it melts perfectly when added to dark chocolate.
9.5
Best sweetener found
Most Useful Review
This is the best sweetener I've ever encountered. It only requires a small amount and doesn’t turn bitter when overused, unlike some others. It has no artificial taste, dissolves easily even in cold liquids, and lasts me nearly a year. I use it in various dishes, from chili to soup. Just don't overuse it, as a little goes a long way!
Folic Acid
8
Folate improves cold agglutinin anemia
Coexistence of Cold Agglutinin and Cryoglobulin in a Patient With Severe Anemia Following COVID-19 Infection.
Most Relevant Research
We explored the intriguing case of a patient battling severe anemia after a COVID-19 infection. This patient exhibited both cold agglutinin and cryoglobulin, revealing some interesting findings when we examined their direct antiglobulin test results.
We noted that the test showed C3d positivity while being immunoglobulin G negative, indicating that the patient did not have evident hemolytic anemia or thrombosis. Interestingly, there was no clinically significant IgM monoclonal gammopathy reported, which suggests that the situation might not be as dire as it seems at first glance.
Treatment involved folic acid supplementation, which led to a noticeable improvement in the patient's anemia. Alongside this, we observed a decrease in the cold agglutination titer, and the direct antiglobulin test turned negative, hinting that folate may play a role in managing cold agglutinin-related issues, though it’s essential to view this within the broader context of other influences.
Despite the persistent cryoglobulinemia, the patient did not experience thrombosis or any significant complications. This case prompts us to carefully consider the use of immunosuppressive therapies for cold-related hematologic disorders following COVID-19, particularly as many factors may be at play in affecting patient outcomes.
We noted that the test showed C3d positivity while being immunoglobulin G negative, indicating that the patient did not have evident hemolytic anemia or thrombosis. Interestingly, there was no clinically significant IgM monoclonal gammopathy reported, which suggests that the situation might not be as dire as it seems at first glance.
Treatment involved folic acid supplementation, which led to a noticeable improvement in the patient's anemia. Alongside this, we observed a decrease in the cold agglutination titer, and the direct antiglobulin test turned negative, hinting that folate may play a role in managing cold agglutinin-related issues, though it’s essential to view this within the broader context of other influences.
Despite the persistent cryoglobulinemia, the patient did not experience thrombosis or any significant complications. This case prompts us to carefully consider the use of immunosuppressive therapies for cold-related hematologic disorders following COVID-19, particularly as many factors may be at play in affecting patient outcomes.
9.5
Life-changing vitamin
Most Useful Review
I am so pleased to have found this vitamin. It has been a life-altering experience for my family and me. My mood has improved, my energy levels have increased, and my immunity against colds is far better. I highly recommend it!
Green Tea Extract
7
Effectiveness of Vitamin C on Colds
Vitamin C for the common cold and pneumonia.
Most Relevant Research
We explored the effects of vitamin C on the common cold and pneumonia by examining a range of studies. Interestingly, research on animals suggests that vitamin C may have protective effects against infections. However, when it comes to preventing colds in the general population, taking more than 1 gram of vitamin C per day didn’t show significant benefits.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
9.5
Cold lifesaver
Most Useful Review
Where was this before? This green tea is a lifesaver on cold, dark winter days. I follow the instructions, and my energy has tripled. There's no better price-quality ratio. I've previously tried Eleutherococ, but the effect was not as evident as with these capsules. I will continue to take more.
Sodium Ascorbate
7
Vitamin C’s mixed efficacy on colds
Vitamin C for the common cold and pneumonia.
Most Relevant Research
We examined the effectiveness of sodium ascorbate, commonly known as vitamin C, for treating colds and pneumonia. While high doses above 1 g/day didn’t prevent colds for the general public, they did show significant benefits for those engaged in heavy exercise, reducing cold incidence by half.
Regular use of 1 g or more daily also helped lessen cold severity by 15%. When taken after cold symptoms appeared, higher doses of 6-8 g/day effectively reduced the duration of colds. However, findings on pneumonia were mixed, suggesting that while there may be some benefit for certain groups, more research is essential for broader applications.
Regular use of 1 g or more daily also helped lessen cold severity by 15%. When taken after cold symptoms appeared, higher doses of 6-8 g/day effectively reduced the duration of colds. However, findings on pneumonia were mixed, suggesting that while there may be some benefit for certain groups, more research is essential for broader applications.
10
Immediate relief
Most Useful Review
The most convenient form of Vitamin C. The effect is immediate at the first signs of a cold. I recommend it to everyone!
Cinnamon Herbs
9.5
Prevents coldness
Most Useful Review
This supplement aids in reviving lost capillaries. I've been drinking it daily for over six months, and remarkably, my hands and feet haven't felt cold this winter. It also boosts blood circulation, benefiting hair growth.
8.3
Positive cold relief
Most Useful Review
Repurchase after observing the effect on cold limbs.
Vitamin Bs
8
Folate improves cold agglutinin anemia
Coexistence of Cold Agglutinin and Cryoglobulin in a Patient With Severe Anemia Following COVID-19 Infection.
Most Relevant Research
We explored the intriguing case of a patient battling severe anemia after a COVID-19 infection. This patient exhibited both cold agglutinin and cryoglobulin, revealing some interesting findings when we examined their direct antiglobulin test results.
We noted that the test showed C3d positivity while being immunoglobulin G negative, indicating that the patient did not have evident hemolytic anemia or thrombosis. Interestingly, there was no clinically significant IgM monoclonal gammopathy reported, which suggests that the situation might not be as dire as it seems at first glance.
Treatment involved folic acid supplementation, which led to a noticeable improvement in the patient's anemia. Alongside this, we observed a decrease in the cold agglutination titer, and the direct antiglobulin test turned negative, hinting that folate may play a role in managing cold agglutinin-related issues, though it’s essential to view this within the broader context of other influences.
Despite the persistent cryoglobulinemia, the patient did not experience thrombosis or any significant complications. This case prompts us to carefully consider the use of immunosuppressive therapies for cold-related hematologic disorders following COVID-19, particularly as many factors may be at play in affecting patient outcomes.
We noted that the test showed C3d positivity while being immunoglobulin G negative, indicating that the patient did not have evident hemolytic anemia or thrombosis. Interestingly, there was no clinically significant IgM monoclonal gammopathy reported, which suggests that the situation might not be as dire as it seems at first glance.
Treatment involved folic acid supplementation, which led to a noticeable improvement in the patient's anemia. Alongside this, we observed a decrease in the cold agglutination titer, and the direct antiglobulin test turned negative, hinting that folate may play a role in managing cold agglutinin-related issues, though it’s essential to view this within the broader context of other influences.
Despite the persistent cryoglobulinemia, the patient did not experience thrombosis or any significant complications. This case prompts us to carefully consider the use of immunosuppressive therapies for cold-related hematologic disorders following COVID-19, particularly as many factors may be at play in affecting patient outcomes.
10
Strengthened immunity
Most Useful Review
Good day, I believe we need vitamin B12. It's particularly important for those not eating meat, the elderly, or anyone run down. This vitamin seems to be well absorbed. Remarkably, I haven't caught a cold this autumn; my immunity feels strengthened. My memory has improved, and I feel more alert and better at learning. My joints are more mobile without pain, and my sleep has improved; I don't wake at night. This vitamin has stabilised my emotional wellbeing, and I feel much calmer.
Dha
9
DHA enhances calf growth, reduces inflammation
Effects of fat source in calf starter on growth performance, blood fatty acid profiles, and inflammatory markers during cold season.
Most Relevant Research
We investigated how different fat sources in calf starter diets influence growth, health, and inflammation, particularly during cold weather. Our study involved 48 Holstein calves, divided into four diet groups: one without added fat, one with calcium-salts of soybean oil (Ca-SBO), another with calcium-salts of fish oil (Ca-FO), and a mix of both.
We found that calves fed the Ca-FO diet, which contains DHA and other beneficial fats, had significantly better growth performance and higher final body weights compared to the other groups. In fact, these calves showed enhanced feed efficiency and increased average daily gains, suggesting that DHA, often found in fish oils, plays a crucial role in improving growth in challenging cold conditions.
Furthermore, the calves on the Ca-FO diet exhibited lower levels of inflammatory markers compared to their counterparts, which indicates a potential of DHA in reducing inflammation, a common issue in cold environments. In contrast, the Ca-SBO group had higher levels of certain fats and inflammation markers, pointing to the advantages of including DHA in calf diets during cold seasons.
Overall, our findings suggest that enriching calf diets with DHA not only supports better growth in cold climates but also helps in managing inflammation.
We found that calves fed the Ca-FO diet, which contains DHA and other beneficial fats, had significantly better growth performance and higher final body weights compared to the other groups. In fact, these calves showed enhanced feed efficiency and increased average daily gains, suggesting that DHA, often found in fish oils, plays a crucial role in improving growth in challenging cold conditions.
Furthermore, the calves on the Ca-FO diet exhibited lower levels of inflammatory markers compared to their counterparts, which indicates a potential of DHA in reducing inflammation, a common issue in cold environments. In contrast, the Ca-SBO group had higher levels of certain fats and inflammation markers, pointing to the advantages of including DHA in calf diets during cold seasons.
Overall, our findings suggest that enriching calf diets with DHA not only supports better growth in cold climates but also helps in managing inflammation.
8.8
No colds experienced
Most Useful Review
We take omega as a family. For adults, we specifically opt for this company's omega. The dosage is good, as it is convenient to take one capsule daily. Previously, we frequently fell ill, but since we started taking omega and D3, we have forgotten what a cold is, or we only experience it mildly. One jar lasts us three months. The price and quality match well.
Vitamin D
5
Vitamin D and cold symptoms
The Effects of Vitamin D Supplementation on Respiratory Infections in Children under 6 Years Old: A Systematic Review.
Most Relevant Research
We explored the effects of vitamin D supplementation on respiratory infections, particularly colds, in children under six years old. By examining various studies published until February 2023, we observed diverse findings, with some studies reporting benefits while others found no significant advantage. Overall, eight studies were included, with a total of 2,189 children assessed.
While a few studies indicated that low vitamin D levels might be linked to an increased risk of respiratory infections, only one study specifically noted that children who took 800 IU of vitamin D daily for three months experienced fewer mild respiratory symptoms and recovered more quickly. However, a significant number of studies showed no notable differences in the rates or severity of colds when vitamin D supplementation was used.
In essence, the evidence regarding vitamin D's role in preventing or effectively treating colds in young children is still unclear. We did find some indications that certain doses, like 80 IU/kg/day, may help reduce acute respiratory infection risks, but most research highlighted only minor benefits, such as quicker recovery rather than preventing infections. Variability in study design and supplementation protocols contributed to these inconclusive results, highlighting the need for further research.
While a few studies indicated that low vitamin D levels might be linked to an increased risk of respiratory infections, only one study specifically noted that children who took 800 IU of vitamin D daily for three months experienced fewer mild respiratory symptoms and recovered more quickly. However, a significant number of studies showed no notable differences in the rates or severity of colds when vitamin D supplementation was used.
In essence, the evidence regarding vitamin D's role in preventing or effectively treating colds in young children is still unclear. We did find some indications that certain doses, like 80 IU/kg/day, may help reduce acute respiratory infection risks, but most research highlighted only minor benefits, such as quicker recovery rather than preventing infections. Variability in study design and supplementation protocols contributed to these inconclusive results, highlighting the need for further research.
9.5
Less frequent colds
Most Useful Review
After regularly taking vitamin D3, I’ve noticed that both my child and I rarely catch a cold. My daughter used to attend kindergarten without a break from October to February, but now, she’s far healthier. I generally feel more cheerful as well. When I stop taking vitamin D3, I often experience discomfort in my back, but as soon as I resume, the pain disappears almost immediately. This improvement truly delights me.
B12
8
Vitamin B12 shows cold pain relief
The effects of vitamin B12 and diclofenac and their combination on cold and mechanical allodynia in a neuropathic pain model in rats.
Most Relevant Research
We explored the potential effects of vitamin B12 on cold sensitivity in a study using rats with induced neuropathic pain. The focus was to see whether vitamin B12, both alone and in combination with the pain reliever diclofenac, could alleviate cold and mechanical allodynia—a condition where non-painful stimuli are perceived as painful.
In our approach, we administered vitamin B12 in varying doses over ten consecutive days following nerve injury. What we discovered was quite telling. Higher doses of vitamin B12 (50, 100, and 200 µg kg(-1)) led to a reduction in cold sensitivity. However, when using a lower, subanalgesic dose (25 µg kg(-1)), vitamin B12 did not significantly impact pain responses when paired with low doses of diclofenac.
As we adjusted the vitamin B12 dosage to a more effective level (100 µg kg(-1)), we noticed an improvement in pain relief compared to diclofenac alone. These findings suggest that vitamin B12 could have a positive effect on alleviating cold-related pain in neuropathic conditions, especially when used at appropriate doses.
In our approach, we administered vitamin B12 in varying doses over ten consecutive days following nerve injury. What we discovered was quite telling. Higher doses of vitamin B12 (50, 100, and 200 µg kg(-1)) led to a reduction in cold sensitivity. However, when using a lower, subanalgesic dose (25 µg kg(-1)), vitamin B12 did not significantly impact pain responses when paired with low doses of diclofenac.
As we adjusted the vitamin B12 dosage to a more effective level (100 µg kg(-1)), we noticed an improvement in pain relief compared to diclofenac alone. These findings suggest that vitamin B12 could have a positive effect on alleviating cold-related pain in neuropathic conditions, especially when used at appropriate doses.
9.5
Pain relief achieved
Most Useful Review
It worked well for pain in my spinal cord due to cervical spondylosis myelopathy. When I was having trouble sleeping and feeling emotional, I turned to vitamin B12 for nerve repair. After taking one capsule daily, the pain in my neck and shoulder blades eased within a month, and the numbness in my fingers vanished. Most notably, the feeling of cold also disappeared! I’m gradually returning to my pre-illness condition, and I plan to continue this treatment.
Medicinal Teas
5
Evaluating elderberry for colds
Elderberry for prevention and treatment of viral respiratory illnesses: a systematic review.
Most Relevant Research
We investigated the potential of elderberry as a treatment to help with cold symptoms. In our review, we looked at several clinical trials that specifically examined elderberry's effectiveness in reducing the severity and duration of cold illnesses.
While elderberry might not significantly lower the risk of catching a cold, we found evidence suggesting it could help decrease how long and how severely colds affect us. The data on this was uncertain, though, so we can't say with complete confidence that elderberry is a miracle cure.
Additionally, when comparing elderberry with antiviral medications, such as oseltamivir, there are hints that an elderberry product might lead to fewer complications and side effects for individuals dealing with influenza. It's also worth noting that while elderberry may influence some inflammatory markers, it does not seem to spur excessive immune responses that could lead to negative health outcomes like a “cytokine storm.”
In conclusion, elderberry appears to be a safe option for addressing viral respiratory issues, including colds. However, more research is needed to clearly establish its benefits and any potential downsides.
While elderberry might not significantly lower the risk of catching a cold, we found evidence suggesting it could help decrease how long and how severely colds affect us. The data on this was uncertain, though, so we can't say with complete confidence that elderberry is a miracle cure.
Additionally, when comparing elderberry with antiviral medications, such as oseltamivir, there are hints that an elderberry product might lead to fewer complications and side effects for individuals dealing with influenza. It's also worth noting that while elderberry may influence some inflammatory markers, it does not seem to spur excessive immune responses that could lead to negative health outcomes like a “cytokine storm.”
In conclusion, elderberry appears to be a safe option for addressing viral respiratory issues, including colds. However, more research is needed to clearly establish its benefits and any potential downsides.
9.5
Essential for colds
Most Useful Review
Wonderful natural collection is essential for colds, instantly puts you on your feet. The taste is pleasant. I always keep it in my medicine cabinet. No pills are necessary if you also take vitamin C and Zinc. All health! Thanks for the likes 👍🏼
Iron
8
Iron improves cold tolerance
Dihydroporphyrin iron (III) enhances low temperature tolerance by increasing carbon and nitrogen metabolism in .
Most Relevant Research
We investigated how dihydroporphyrin iron (DH-Fe) acts as a plant growth regulator, particularly in enhancing cold tolerance. Our research focused on plants that are usually sensitive to low temperatures, finding that DH-Fe plays a vital role in helping these plants cope with cold stress by using different concentrations of this treatment.
Through our study, we applied varying levels of DH-Fe to see how it impacts carbon and nitrogen metabolism, as well as oxidative stress responses, when plants were exposed to low temperatures. Notably, we observed that DH-Fe significantly reduces oxidative stress and other harmful effects associated with cold exposure. For instance, it reduced certain sugars while simultaneously boosting the activity of enzymes crucial for sugar breakdown and nitrogen assimilation.
Among the various findings, we noted that a concentration of 20 μg·L of DH-Fe was particularly effective, improving the overall health and resilience of the plants against low temperatures. This suggests that by applying the right amount of iron, we can potentially mitigate the negative effects of cold weather on sensitive plant species, providing a fresh perspective on how to enhance cold tolerance through nutrient management.
Overall, our findings shine a light on how incorporating iron into agricultural practices might be a practical strategy for improving plant resilience to cold stress.
Through our study, we applied varying levels of DH-Fe to see how it impacts carbon and nitrogen metabolism, as well as oxidative stress responses, when plants were exposed to low temperatures. Notably, we observed that DH-Fe significantly reduces oxidative stress and other harmful effects associated with cold exposure. For instance, it reduced certain sugars while simultaneously boosting the activity of enzymes crucial for sugar breakdown and nitrogen assimilation.
Among the various findings, we noted that a concentration of 20 μg·L of DH-Fe was particularly effective, improving the overall health and resilience of the plants against low temperatures. This suggests that by applying the right amount of iron, we can potentially mitigate the negative effects of cold weather on sensitive plant species, providing a fresh perspective on how to enhance cold tolerance through nutrient management.
Overall, our findings shine a light on how incorporating iron into agricultural practices might be a practical strategy for improving plant resilience to cold stress.
9.5
No colds anymore
Most Useful Review
I would like to continue using this product in the future as it is gentle on the body and free from unnecessary ingredients! I take it with vitamin C, and I'm surprised that I haven't caught colds, even when my children have!
Face Mist
9.5
Refreshing mist
Most Useful Review
I've purchased it three times because it provides excellent freshness and radiance. I keep it in the fridge until it’s cold and often spray it throughout the day. It’s terrible how addictive it is!
9.5
Soothing hydration
Most Useful Review
I really like this water. I've ordered it several times and have enough for six months. It refreshes and soothes my skin well. I apply it before my serum, and whenever my face feels overly warm after a long walk in the cold, it provides instant relief.
Astragalus
7
Astragalus-root shows mixed effects
Effects of Chinese herbal medicine and cold exposure on plasma glucose, leucine and energy metabolism in sheep.
Most Relevant Research
We conducted an experiment to evaluate the effects of a traditional Chinese herbal medicine mixture, including astragalus-root, when sheep were exposed to cold temperatures. The study involved feeding four sheep either a mixed hay diet or hay supplemented with 2% of the herbal mix over two periods, during which they experienced a controlled cold exposure for five days.
While we observed some benefits of the herbal treatment, specifically regarding nitrogen balance and energy metabolism, the results showed that the metabolism of plasma leucine—important for protein synthesis—remained unchanged in cold conditions. Although plasma glucose and energy metabolism improved with both the herbal diet and cold exposure, the herbal mixture alone did not significantly enhance the sheep's ability to cope with cold stress in terms of leucine metabolism.
Overall, while astragalus-root mixed with other herbs seems beneficial for certain metabolic processes, it did not provide clear advantages in terms of cold adaptation for the sheep in our study.
While we observed some benefits of the herbal treatment, specifically regarding nitrogen balance and energy metabolism, the results showed that the metabolism of plasma leucine—important for protein synthesis—remained unchanged in cold conditions. Although plasma glucose and energy metabolism improved with both the herbal diet and cold exposure, the herbal mixture alone did not significantly enhance the sheep's ability to cope with cold stress in terms of leucine metabolism.
Overall, while astragalus-root mixed with other herbs seems beneficial for certain metabolic processes, it did not provide clear advantages in terms of cold adaptation for the sheep in our study.
10
No colds experienced
Most Useful Review
It strengthens the immune system remarkably well! It helped me and my children immensely; we really experienced no colds! Astragalus contains numerous trace elements and essential vitamins needed for humans, making it a valuable supplement.
Calcium Citrate
5
Vitamin D and cold symptoms
The Effects of Vitamin D Supplementation on Respiratory Infections in Children under 6 Years Old: A Systematic Review.
Most Relevant Research
We explored the effects of vitamin D supplementation on respiratory infections, particularly colds, in children under six years old. By examining various studies published until February 2023, we observed diverse findings, with some studies reporting benefits while others found no significant advantage. Overall, eight studies were included, with a total of 2,189 children assessed.
While a few studies indicated that low vitamin D levels might be linked to an increased risk of respiratory infections, only one study specifically noted that children who took 800 IU of vitamin D daily for three months experienced fewer mild respiratory symptoms and recovered more quickly. However, a significant number of studies showed no notable differences in the rates or severity of colds when vitamin D supplementation was used.
In essence, the evidence regarding vitamin D's role in preventing or effectively treating colds in young children is still unclear. We did find some indications that certain doses, like 80 IU/kg/day, may help reduce acute respiratory infection risks, but most research highlighted only minor benefits, such as quicker recovery rather than preventing infections. Variability in study design and supplementation protocols contributed to these inconclusive results, highlighting the need for further research.
While a few studies indicated that low vitamin D levels might be linked to an increased risk of respiratory infections, only one study specifically noted that children who took 800 IU of vitamin D daily for three months experienced fewer mild respiratory symptoms and recovered more quickly. However, a significant number of studies showed no notable differences in the rates or severity of colds when vitamin D supplementation was used.
In essence, the evidence regarding vitamin D's role in preventing or effectively treating colds in young children is still unclear. We did find some indications that certain doses, like 80 IU/kg/day, may help reduce acute respiratory infection risks, but most research highlighted only minor benefits, such as quicker recovery rather than preventing infections. Variability in study design and supplementation protocols contributed to these inconclusive results, highlighting the need for further research.
9.5
Pain-free experience
Most Useful Review
The dentist suggested a course of calcium citrate with vitamin D3 to improve my enamel. I noticed a remarkable positive effect: my sensitive tooth enamel used to react vigorously to sweet-hot-cold, but after using this supplement, I've forgotten about my discomfort. My teeth no longer hurt or ache.