Probiotics
9.5
Saccharomyces improves acne treatment
[Treatment of acne with a yeast preparation].
Most Relevant Research
We explored how Saccharomyces cerevisiae Hansen CBS 5926, also known as Perenterol, affects acne in a randomized, double-blind study with 139 participants.
The study revealed impressive results: approximately 74.3% of those treated reported good or very good outcomes, compared to just 21.7% in the placebo group.
More than 80% of patients who received the yeast preparation saw substantial improvement or healing, while only 26% in the placebo group experienced similar results.
Notably, there were no significant side effects reported in either group, making this treatment an increasingly popular option for those battling acne.
The study revealed impressive results: approximately 74.3% of those treated reported good or very good outcomes, compared to just 21.7% in the placebo group.
More than 80% of patients who received the yeast preparation saw substantial improvement or healing, while only 26% in the placebo group experienced similar results.
Notably, there were no significant side effects reported in either group, making this treatment an increasingly popular option for those battling acne.
9.5
Effective for acne
Most Useful Review
Jarrow Formulas saccharomycetes are an excellent alternative to probiotics based on bacteria. They pass through the gastrointestinal tract safely and effectively treat acne, among other conditions. I always take them on my travels instead of bacterial probiotics. Highly recommended!
MSM
9.5
Acne improvement
Most Useful Review
Edited my review, please like ❤️ and share my experience. After two weeks, I noticed significant improvement; my acne almost vanished while taking MSM. Even my hair seemed healthier. The quality is excellent, and the formula is suitable for those over 18. I was hoping for clearer skin, and it seems effective. Support me in sharing this!
9.5
Clearer skin
Most Useful Review
I take sulphur supplements for hair and skin; my teenage brother also takes zinc for facial acne. His face is much clearer now, with nearly all acne gone.
9.5
Acne resolved
Most Useful Review
This supplement improved my overall immunity. After completing the course, my skin issues, notably acne, vanished, and my previously brittle nails and hair health improved significantly. I take one pill a day, and I've experienced no adverse tastes or odour.
9.5
Acne improvement
Most Useful Review
Excellent vitamin, it helped combat acne. After starting the supplement, my skin cleared up significantly. My hair has also become shinier and thicker.
Multivitamins
9.5
Cleared skin
Most Useful Review
Excellent! My skin has improved, the acne has disappeared, and my hair is now silky.
9.5
Improved complexion
Most Useful Review
I discovered I had a vitamin deficiency. I usually prefer meat and rice and neglect vegetables. In my 40s, this neglect showed on my face. To combat it, I began taking vitamins B and C in the morning and evening, as well as A and E at night. My complexion improved, with no acne and smaller pores. I felt rejuvenated. It’s clear that internal changes are essential for real improvement.
Vitamin B Complex
10
No acne
Most Useful Review
Great effect on acne! I initially took this for my health, but it significantly improved my acne. After two weeks, my skin was clear. I believe those struggling with rough skin should certainly try it. I've tried other vitamins, but this one proved most effective. I hope it helps! 😆
10
Effective for acne
Most Useful Review
I found it effective against acne. I started taking it for my health, but it noticeably improved my skin. After about two weeks, my face was clear of acne. I’ve tried other multivitamins, but this one worked best. If you struggle with rough skin, I recommend giving it a try.
Oregano
9.5
Probiotics and Oregano Combat Acne
Additive Effects of Natural Plant Extracts/Essential Oils and Probiotics as an Antipathogenic Topical Skin Patch Solution for Acne and Eczema.
Most Relevant Research
We explored the potential of oregano essential oil (EO) and probiotics in battling acne. Our study focused on how these natural ingredients could work together to inhibit the growth of bacteria associated with acne vulgaris.
After evaluating several probiotic strains and natural extracts, we found that one specific probiotic, PCB003, was able to effectively inhibit the bacteria responsible for acne. Among the various EOs tested, oregano EO demonstrated the most promising results, especially since it did not harm probiotic growth.
We designed topical patches using alginate and trehalose, finding that these materials effectively preserved the probiotics. When combined with PCB003 and PCB011, the patches not only inhibited bacterial growth significantly but also outperformed standard over-the-counter acne patches.
Notably, when we incorporated oregano EO into the patches, the results were even better. The patches with 30% oregano EO showed an impressive increase in the inhibition zone, achieving substantial inhibition against acne-causing bacteria. Overall, our results suggest that combining probiotics with oregano EO could provide a powerful, natural solution for acne treatment.
After evaluating several probiotic strains and natural extracts, we found that one specific probiotic, PCB003, was able to effectively inhibit the bacteria responsible for acne. Among the various EOs tested, oregano EO demonstrated the most promising results, especially since it did not harm probiotic growth.
We designed topical patches using alginate and trehalose, finding that these materials effectively preserved the probiotics. When combined with PCB003 and PCB011, the patches not only inhibited bacterial growth significantly but also outperformed standard over-the-counter acne patches.
Notably, when we incorporated oregano EO into the patches, the results were even better. The patches with 30% oregano EO showed an impressive increase in the inhibition zone, achieving substantial inhibition against acne-causing bacteria. Overall, our results suggest that combining probiotics with oregano EO could provide a powerful, natural solution for acne treatment.
8.8
Effective antibiotic
Most Useful Review
I use oregano oil as a natural antibiotic against cystic acne, and it's highly effective when paired with Sovereign Silver. It benefits gut health and those suffering from SIBO, too. Gaia is reputable for high-grade supplements, and I recommend this product wholeheartedly.
Inositol
8
Inositol aids acne in PCOS
Comparison of Clinical, Metabolic and Hormonal Effects of Metformin Versus Combined Therapy of Metformin With Myoinositol Plus D-Chiro-Inositol in Women With Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial.
Most Relevant Research
We embarked on a study to examine the effectiveness of inositol when used alongside metformin for women struggling with acne related to polycystic ovary syndrome (PCOS). Our research involved a randomized trial with two groups: one group received metformin alone, while the other combined metformin with myoinositol and D-chiro-inositol over a six-month period.
After analyzing the results, we observed that the group receiving the combined treatment showed a statistically significant improvement in their acne scores. Notably, the group taking both metformin and inositol experienced better skin outcomes compared to the group on metformin alone. Furthermore, additional metabolic and hormonal improvements were noted in this combined therapy group as well.
However, it’s essential to point out that our study did not isolate the effects of inositol alone on acne. So, while the combination showed promise for improving acne among women with PCOS, we're not claiming that inositol on its own is a guaranteed solution. Further research with a larger sample size and a focus on inositol's individual impact will be crucial for confirming these findings.
After analyzing the results, we observed that the group receiving the combined treatment showed a statistically significant improvement in their acne scores. Notably, the group taking both metformin and inositol experienced better skin outcomes compared to the group on metformin alone. Furthermore, additional metabolic and hormonal improvements were noted in this combined therapy group as well.
However, it’s essential to point out that our study did not isolate the effects of inositol alone on acne. So, while the combination showed promise for improving acne among women with PCOS, we're not claiming that inositol on its own is a guaranteed solution. Further research with a larger sample size and a focus on inositol's individual impact will be crucial for confirming these findings.
9.5
Acne prevention benefits
Most Useful Review
Myo-inositol has proven effective for PCOS and is essential in managing beauty and youth. I've noticed improvements in my skin, as it prevents acne and promotes hair growth. Additionally, it aids in sleep and mood. After taking it, I experienced fewer breakouts, and it significantly improved my overall health alongside fertility, making it a vital supplement to my routine.
Oleuropein
8.8
Helps with acne
Most Useful Review
This product has saved me from flu and effectively calms my cystic acne. I took two capsules daily, and while others suffered from flu, I remained unaffected. It also aids in reducing inflammation, helping my wounds heal faster.
9.5
Acne treatment success
Most Useful Review
These capsules are effective for tackling acne, and I've seen great results.
Urtica Dioica
10
Effective acne solution
Most Useful Review
My salvation! Since adolescence, I suffered from acne with no relief from diet, creams, or specialists. After watching Dr. Berg, I tried nettle root and within 4 days my skin cleared up! I'm amazed by the results after just 2 capsules daily. Such suffering and such a simple solution I found! Take it; you won't regret it!
9.5
Effective supplement
Most Useful Review
This is an effective supplement for hyperandrogenism, acne, and androgenetic alopecia. It significantly reduces androgens, especially in combination with myo-inositol and saw palmetto. I'm pleased with its affordability and results!
Vitamin A
7
Vitamin A impacts acne and eyes
Oral Isotretinoin-Associated Ocular Effects and Risk Factors: A Cross-Sectional Study.
Most Relevant Research
We analyzed how oral isotretinoin, a vitamin A derivative, impacts acne treatment and ocular health. This study included 489 participants from the Jazan region, where we used an online questionnaire to gather data on symptoms experienced during isotretinoin therapy.
As we learned, many participants faced issues such as dry eyes and blurry vision, which are known side effects of the treatment. Over half of current users reported severe ocular symptoms, highlighting the importance of monitoring eye health for those undergoing this acne treatment.
Notably, individuals who used contact lenses or were on higher doses of isotretinoin experienced worse symptoms. These findings remind us of the necessity to assess individual risk factors before starting treatment. Overall, while vitamin A in isotretinoin effectively addresses acne, it also brings potential ocular concerns that should not be overlooked.
As we learned, many participants faced issues such as dry eyes and blurry vision, which are known side effects of the treatment. Over half of current users reported severe ocular symptoms, highlighting the importance of monitoring eye health for those undergoing this acne treatment.
Notably, individuals who used contact lenses or were on higher doses of isotretinoin experienced worse symptoms. These findings remind us of the necessity to assess individual risk factors before starting treatment. Overall, while vitamin A in isotretinoin effectively addresses acne, it also brings potential ocular concerns that should not be overlooked.
8.8
Cleared acne
Most Useful Review
It helps me with subcutaneous acne and milia. I take this vitamin in the autumn when the sun is less intense. I appreciate that the vitamin is in small, easy-to-swallow capsules. There were no side effects, and it was well packaged with protective sealing.
Silybum Marianum
7
Effectiveness of Silybum marianum on acne
Tolerability and effectiveness of a dermocosmetic product containing Silybum marianum fruit extract in adolescents and young adults with acne-prone skin: An international, phase IV, longitudinal study.
Most Relevant Research
We examined the effectiveness and tolerance of a dermocosmetic product containing Silybum marianum fruit extract in treating acne in adolescents and young adults. In an international study with over 4,200 participants aged 12 to 25, the product was used twice daily for 8 to 12 weeks. It was applied alone, after medical therapy, or alongside other treatments.
While the product showed promise in managing acne, its role appears more supportive than curative, helping to reduce reliance on traditional anti-acne medications.
While the product showed promise in managing acne, its role appears more supportive than curative, helping to reduce reliance on traditional anti-acne medications.
9.5
Transformed my skin
Most Useful Review
This product transformed my face after 10 years of struggling with acne. I took Silymarin to support my liver while not always maintaining a healthy diet. It significantly improved my facial skin condition, particularly regarding rosacea and inflammation.
Zinc
8
Zinc treatment shows promise for acne
Comparative transcriptome analysis of acne vulgaris, rosacea, and hidradenitis suppurativa supports high-dose dietary zinc as a therapeutic agent.
Most Relevant Research
We explored how zinc treatment may help with inflammatory skin conditions like acne vulgaris, rosacea, and hidradenitis suppurativa. These conditions can appear quite similar, which makes diagnosing them a bit tricky. By examining gene expression data across these three disorders, we noticed that certain zinc-binding proteins were consistently elevated in all cases.
Our hypothesis centers around these proteins possibly sequestering zinc, which could promote inflammation due to local zinc deficiency. To investigate this further, we identified high-dose dietary zinc as a potential therapeutic option. This was tested and validated in an acne mouse model, showing promising results for its effectiveness in reducing the inflammation associated with acne.
Although the study specifically highlighted the isolated effect of zinc, it strongly suggests that incorporating high doses of dietary zinc might offer a new avenue for treatment. This could be an encouraging option for those struggling with acne, pointing to a novel approach grounded in scientific findings.
Our hypothesis centers around these proteins possibly sequestering zinc, which could promote inflammation due to local zinc deficiency. To investigate this further, we identified high-dose dietary zinc as a potential therapeutic option. This was tested and validated in an acne mouse model, showing promising results for its effectiveness in reducing the inflammation associated with acne.
Although the study specifically highlighted the isolated effect of zinc, it strongly suggests that incorporating high doses of dietary zinc might offer a new avenue for treatment. This could be an encouraging option for those struggling with acne, pointing to a novel approach grounded in scientific findings.
9.5
Clear skin achieved
Most Useful Review
Zinc has transformed my skin! It aids in renewing skin cells and collagen formation, reducing acne and dryness while helping to heal wounds. I've noticed fewer pimples and stronger hair after a month of use. Unlike other zinc supplements, this one doesn't make me feel unwell. I wholeheartedly recommend it!
Flax Seed Oil
9.5
Effective for acne
Most Useful Review
This oil is fantastic for my skin. I started taking three capsules daily with food, and after a week, my face, which had been plagued with acne, improved significantly. I won't be without it.
10
Acne-free skin
Most Useful Review
A lifesaver for my skin! I began taking it and my acne disappeared completely. The quality is excellent, plus it helps lower cholesterol and improves hair growth. It has a neutral taste, and the ingredients are very pure. I absolutely loved it.
Tumeric
9
Curcumin affects acne treatment efficacy
Utilizing the photodynamic properties of curcumin to disrupt biofilms in Cutibacterium acnes: A promising approach for treating acne.
Most Relevant Research
We examined the effectiveness of curcumin, a compound found in turmeric, in tackling acne by disrupting the biofilms formed by Cutibacterium acnes (C.acnes), a key player in acne development. The study primarily focused on how curcumin combined with light therapy could provide a promising alternative treatment, especially in light of rising antibiotic resistance.
Following established guidelines, we tested 25 clinical strains of C.acnes against various antibiotics and curcumin. Our findings revealed that while C.acnes exhibited substantial resistance to most antibiotics, curcumin showed robust potential. It was found to effectively reduce the survival rates of planktonic C.acnes, and significantly disrupt the three-dimensional structure of biofilms when used in conjunction with blue light therapy.
This suggests that curcumin photodynamic therapy could be a viable option for treating acne, particularly for individuals facing challenges with antibiotic-resistant bacteria. Overall, we observed encouraging results that highlight curcumin's potential in acne treatments and its role in combating stubborn biofilm formations.
Following established guidelines, we tested 25 clinical strains of C.acnes against various antibiotics and curcumin. Our findings revealed that while C.acnes exhibited substantial resistance to most antibiotics, curcumin showed robust potential. It was found to effectively reduce the survival rates of planktonic C.acnes, and significantly disrupt the three-dimensional structure of biofilms when used in conjunction with blue light therapy.
This suggests that curcumin photodynamic therapy could be a viable option for treating acne, particularly for individuals facing challenges with antibiotic-resistant bacteria. Overall, we observed encouraging results that highlight curcumin's potential in acne treatments and its role in combating stubborn biofilm formations.
9
Improved skin quality
Most Useful Review
Friendly for women during menstruation, curcumin positively impacts skin quality. After using it for over a year, I've noticed improvements in my acne and faster muscle recovery. It also helps lessen discomfort and abdominal pain during my cycle. This brand is reliable.
Evening Primrose
9
PMS symptom relief
Most Useful Review
Excellent! I take one capsule daily after breakfast for my acne, and I've experienced no PMS symptoms, less emotional fluctuation, and much reduced pain during periods. I've ordered a second bottle, hoping for further skin improvements.
9.5
Cleared skin
Most Useful Review
This product is fantastic! Although it's aimed at menopausal symptoms, it has effectively reduced my hormonal acne. I’ve been taking it for about three weeks with no breakouts so far!
Fish Oil
9
Docosahexaenoic acid reduces acne risk
The causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study.
Most Relevant Research
We investigated the relationship between docosahexaenoic acid (DHA), a type of polyunsaturated fatty acid (PUFA), and the occurrence of acne. Using a method called Mendelian randomization, we looked at how genetic variations associated with DHA might influence acne development in large groups of participants, including over 115,000 individuals from the UK and nearly 364,000 of Finnish ancestry.
Our findings revealed that higher levels of DHA are actually linked to a lower risk of developing acne. Specifically, we found that a significant increase in DHA levels or its proportion compared to total fatty acids corresponded with a reduced likelihood of acne. In contrast, higher levels of linoleic acid (LA), another type of PUFA, were associated with an increased acne risk.
This suggests that balancing our intake of these fatty acids might be important for skin health. Notably, the results pointed towards a genetic connection involving the FADS1 gene, which appears to play a role in how these fatty acids affect our skin.
In conclusion, increasing DHA could be beneficial in protecting against acne, while excessive linoleic acid might have the opposite effect. Overall, our study highlights the importance of these fatty acids in understanding acne risk better.
Our findings revealed that higher levels of DHA are actually linked to a lower risk of developing acne. Specifically, we found that a significant increase in DHA levels or its proportion compared to total fatty acids corresponded with a reduced likelihood of acne. In contrast, higher levels of linoleic acid (LA), another type of PUFA, were associated with an increased acne risk.
This suggests that balancing our intake of these fatty acids might be important for skin health. Notably, the results pointed towards a genetic connection involving the FADS1 gene, which appears to play a role in how these fatty acids affect our skin.
In conclusion, increasing DHA could be beneficial in protecting against acne, while excessive linoleic acid might have the opposite effect. Overall, our study highlights the importance of these fatty acids in understanding acne risk better.
8.8
Reduced acne
Most Useful Review
Omega 3 is brilliant, with a convenient dosage. Although the capsule is somewhat large, it is easy to swallow and is absorbed well, leaving no fishy aftertaste. The results are evident; my acne has decreased significantly, and the overall quality of my skin has improved.
Polygonum Cuspidatum Complex
9.5
Acne improvement
Most Useful Review
Excellent! I purchased this to address my acne. After two months of taking it, I'm very pleased with the results.
9.5
Post-acne improvement
Most Useful Review
It greatly helped reduce inflammation and post-acne marks. I took one capsule on an empty stomach, and my skin has improved considerably.
Choline
8
Inositol aids acne in PCOS
Comparison of Clinical, Metabolic and Hormonal Effects of Metformin Versus Combined Therapy of Metformin With Myoinositol Plus D-Chiro-Inositol in Women With Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial.
Most Relevant Research
We embarked on a study to examine the effectiveness of inositol when used alongside metformin for women struggling with acne related to polycystic ovary syndrome (PCOS). Our research involved a randomized trial with two groups: one group received metformin alone, while the other combined metformin with myoinositol and D-chiro-inositol over a six-month period.
After analyzing the results, we observed that the group receiving the combined treatment showed a statistically significant improvement in their acne scores. Notably, the group taking both metformin and inositol experienced better skin outcomes compared to the group on metformin alone. Furthermore, additional metabolic and hormonal improvements were noted in this combined therapy group as well.
However, it’s essential to point out that our study did not isolate the effects of inositol alone on acne. So, while the combination showed promise for improving acne among women with PCOS, we're not claiming that inositol on its own is a guaranteed solution. Further research with a larger sample size and a focus on inositol's individual impact will be crucial for confirming these findings.
After analyzing the results, we observed that the group receiving the combined treatment showed a statistically significant improvement in their acne scores. Notably, the group taking both metformin and inositol experienced better skin outcomes compared to the group on metformin alone. Furthermore, additional metabolic and hormonal improvements were noted in this combined therapy group as well.
However, it’s essential to point out that our study did not isolate the effects of inositol alone on acne. So, while the combination showed promise for improving acne among women with PCOS, we're not claiming that inositol on its own is a guaranteed solution. Further research with a larger sample size and a focus on inositol's individual impact will be crucial for confirming these findings.
9.5
Period regularity
Most Useful Review
For those suffering from polycystic ovaries, I highly recommend this treatment. After two months, my periods returned, chronic pain disappeared, and my acne has improved significantly. Using a higher dosage is more effective; I take two to three tablets daily.
Lactoferrin
9
Lactoferrin reduces acne inflammation
Lactoferrin regulates sebogenesis and inflammation in SZ95 human sebocytes and mouse model of acne.
Most Relevant Research
We aimed to explore how lactoferrin affects acne by testing its anti-inflammatory and anti-lipid properties on human sebaceous gland cells and a mouse model. Using SZ95 cells, we treated them with varying concentrations of lactoferrin to observe its impact on cell viability, lipid content, and gene expression related to fat metabolism and inflammation.
Our tests showed that lactoferrin greatly reduced lipid accumulation in these cells while also lowering levels of inflammatory markers. In the acne mouse model, lactoferrin treatment also significantly reduced inflammation and lipid production. Additionally, it led to a decrease in the number of sebaceous gland cells and increased cell death, providing further evidence of its effectiveness.
We found that lactoferrin treatment resulted in lower protein levels associated with inflammation and lipid synthesis in the mice. Overall, our findings indicate that lactoferrin could play a beneficial role in managing acne by targeting both sebogenesis and inflammation.
Our tests showed that lactoferrin greatly reduced lipid accumulation in these cells while also lowering levels of inflammatory markers. In the acne mouse model, lactoferrin treatment also significantly reduced inflammation and lipid production. Additionally, it led to a decrease in the number of sebaceous gland cells and increased cell death, providing further evidence of its effectiveness.
We found that lactoferrin treatment resulted in lower protein levels associated with inflammation and lipid synthesis in the mice. Overall, our findings indicate that lactoferrin could play a beneficial role in managing acne by targeting both sebogenesis and inflammation.
9.5
Improved acne condition
Most Useful Review
Excellent! After seeing the reviews, I purchased lactoferrin. It has significantly improved my acne, which I didn’t expect, along with enhancing my iron absorption and relieving symptoms of anaemia.
Quercetin
9.5
Very effective remedy
Most Useful Review
I’ve had issues with dermatosis, allergies, and acne for a long time, but this means I no longer worry about my diet. It’s remarkably effective and overall, a brilliant drug.
9.3
Acne improvement
Most Useful Review
This supplement effectively improves my acne-prone skin due to its anti-inflammatory properties. My complexion looks noticeably better after just a few days of use.
Vitamin D3
8
Vitamin D3 positively affects acne
Correlation Between Reduced IL-1β Levels in Acne Lesions and the Decrease in Acne Inflammatory Lesions Following Topical Vitamin D Administration: A Double-Blind Randomized Controlled Trial.
Most Relevant Research
We set out to investigate the effectiveness of topical vitamin D3 in treating acne vulgaris, particularly focusing on its anti-inflammatory effects. To do this, we conducted a well-structured double-blind, randomized, placebo-controlled trial over eight weeks. Participants were divided into two groups—one receiving topical vitamin D3 and the other a placebo—both alongside a common acne treatment known as adapalene.
Throughout the study, we closely monitored the levels of interleukin-1 beta (IL-1β), a pro-inflammatory cytokine often elevated in acne lesions. By using advanced assays, we were able to quantify the decrease in IL-1β alongside observing the reduction in inflammatory lesions over time. What we discovered was promising; the topical application of vitamin D3 not only helped lower IL-1β levels in acne lesions but also contributed to a noticeable decrease in acne severity.
These results suggest that vitamin D3 might play a valuable role in managing acne through its ability to modulate inflammation and improve skin conditions. Therefore, incorporating vitamin D3 into acne treatment regimens could be beneficial for those struggling with this common skin issue.
Throughout the study, we closely monitored the levels of interleukin-1 beta (IL-1β), a pro-inflammatory cytokine often elevated in acne lesions. By using advanced assays, we were able to quantify the decrease in IL-1β alongside observing the reduction in inflammatory lesions over time. What we discovered was promising; the topical application of vitamin D3 not only helped lower IL-1β levels in acne lesions but also contributed to a noticeable decrease in acne severity.
These results suggest that vitamin D3 might play a valuable role in managing acne through its ability to modulate inflammation and improve skin conditions. Therefore, incorporating vitamin D3 into acne treatment regimens could be beneficial for those struggling with this common skin issue.
9.5
Clear skin achieved
Most Useful Review
These vitamins have greatly satisfied my body. Due to my thyroid issues, I often battled acne. Since taking these supplements, I've experienced no breakouts at all, even the minor ones. Overall, my condition has improved significantly.
Vitamin C
9
Vitamin C shows moderate efficacy
Efficacy of tranexamic acid solution versus vitamin C solution after micro-needling in treatment of persistent post acne erythema: a split face clinical and 3DAntera camera comparative study.
Most Relevant Research
We explored the effectiveness of using vitamin C in treating persistent post-acne erythema, which often leaves visible redness after acne has cleared. In this study, participants received microneedling combined with either a 10% vitamin C solution or a tranexamic acid solution. The goal was to see which treatment worked better for reducing redness and improving overall skin appearance.
Four treatment sessions were spaced two weeks apart, followed by assessments two weeks after the final session. We measured improvements using clinical evaluations, 3D imaging technology to analyze blood flow in the skin, and patient feedback.
Our findings indicated that both treatments led to significant improvements in reducing skin redness. However, the tranexamic acid solution yielded even better results compared to vitamin C. Patients reported satisfaction on both sides, but they favored the effects of tranexamic acid more. Notably, any side effects were minimal and temporary.
This study suggests that while vitamin C can be helpful, using microneedling with tranexamic acid may deliver superior results for those struggling with post-acne redness.
Four treatment sessions were spaced two weeks apart, followed by assessments two weeks after the final session. We measured improvements using clinical evaluations, 3D imaging technology to analyze blood flow in the skin, and patient feedback.
Our findings indicated that both treatments led to significant improvements in reducing skin redness. However, the tranexamic acid solution yielded even better results compared to vitamin C. Patients reported satisfaction on both sides, but they favored the effects of tranexamic acid more. Notably, any side effects were minimal and temporary.
This study suggests that while vitamin C can be helpful, using microneedling with tranexamic acid may deliver superior results for those struggling with post-acne redness.
9.5
Effective acne treatment
Most Useful Review
I purchased this vitamin C for acne control, and it has worked wonders! After washing my face with water mixed with the powder, I noticed a significant reduction in acne, and my skin's texture improved. I also drink it, and this is the first supplement I've used that has shown such effective results—I'm keen to continue using it.
Coenzyme Q10
8
Supplement may ease isotretinoin side effects
A dietary supplement to reduce side effects of oral isotretinoin therapy in acne patients.
Most Relevant Research
We undertook a study to see if a dietary supplement containing gamma linolenic acid, vitamin E, vitamin C, beta-carotene, coenzyme Q10, and Vitis Vitifera could help reduce common side effects linked to oral isotretinoin treatment for acne. This treatment is well-known for causing dry skin, redness, and peeling—issues that can make patients less willing to stick with their medication.
To explore this, we worked with 48 patients suffering from nodular acne, splitting them into two groups. One group received isotretinoin alongside the dietary supplement, while the other group only took isotretinoin for a duration of six months. We carefully measured various factors, including acne severity, hydration levels, and skin conditions such as erythema and dryness. We also inquired about how often patients adhered to their prescribed treatment.
Our findings revealed that those who used the dietary supplement experienced fewer side effects compared to those who just took isotretinoin. Specifically, they reported less erythema and dryness, as well as feeling more hydrated overall. Additionally, we noted an increase in treatment adherence in the group that took the supplement. Thanks to its antioxidant and moisturizing properties, this dietary supplement could indeed be a helpful addition for anyone undergoing isotretinoin therapy, making the journey a bit easier for patients.
To explore this, we worked with 48 patients suffering from nodular acne, splitting them into two groups. One group received isotretinoin alongside the dietary supplement, while the other group only took isotretinoin for a duration of six months. We carefully measured various factors, including acne severity, hydration levels, and skin conditions such as erythema and dryness. We also inquired about how often patients adhered to their prescribed treatment.
Our findings revealed that those who used the dietary supplement experienced fewer side effects compared to those who just took isotretinoin. Specifically, they reported less erythema and dryness, as well as feeling more hydrated overall. Additionally, we noted an increase in treatment adherence in the group that took the supplement. Thanks to its antioxidant and moisturizing properties, this dietary supplement could indeed be a helpful addition for anyone undergoing isotretinoin therapy, making the journey a bit easier for patients.
9.5
Reduced acne
Most Useful Review
I found L-cysteine and vitamins effective together, as my skin has lightened, and my acne has greatly reduced!
Vitamin Bs
5
Vitamin B12 deficiency linked to acne
The Relationship Between Nutritional Anemia and Acne: A Case-Control Study.
Most Relevant Research
We delved into the relationship between nutritional anemia, specifically vitamin B12 deficiency, and acne among young individuals in the Qassim Region of Saudi Arabia. Utilizing a case-control study design, we compared a group of people with acne to a control group of similar age and demographics. Our research involved Electronic Health Records from a local outpatient department, which allowed us to analyze a broad set of data.
Throughout our investigation, we found that those suffering from acne had a noticeably higher rate of vitamin B12 deficiency—38.6% in the acne group compared to the control group. However, while we saw this correlation, we did not establish a significant relationship between overall vitamin B12 levels and various blood parameters related to anemia. This means that although vitamin B12 deficiency was more prevalent in those with acne, it doesn’t necessarily imply that treating acne specifically with vitamin B12 will yield positive results.
Ultimately, our findings open the door for further investigation into how nutritional factors, particularly vitamin B12, might influence acne severity or development. We believe additional studies are necessary to confirm the possible connections we've observed and to explore potential treatment pathways.
Throughout our investigation, we found that those suffering from acne had a noticeably higher rate of vitamin B12 deficiency—38.6% in the acne group compared to the control group. However, while we saw this correlation, we did not establish a significant relationship between overall vitamin B12 levels and various blood parameters related to anemia. This means that although vitamin B12 deficiency was more prevalent in those with acne, it doesn’t necessarily imply that treating acne specifically with vitamin B12 will yield positive results.
Ultimately, our findings open the door for further investigation into how nutritional factors, particularly vitamin B12, might influence acne severity or development. We believe additional studies are necessary to confirm the possible connections we've observed and to explore potential treatment pathways.
8.3
Skin condition improved
Most Useful Review
I bought this brand with B12 and feel it has improved my skin condition; I no longer suffer from acne. The effects are noticeable, and I usually take them after breakfast.
Omega 3
9
Investigating omega-3 effects on acne
The causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study.
Most Relevant Research
We investigated the connection between omega-3 fatty acids, particularly docosahexaenoic acid (DHA), and the risk of developing acne. By analyzing data from over 478,000 participants, we used a method called Mendelian randomization, which allows us to estimate causal relationships based on genetic information related to omega-3 consumption.
Our findings highlighted that higher levels of DHA were associated with a lower risk of acne. Specifically, a significant reduction in acne risk was observed with increased DHA levels and its ratio to total fatty acids. On the other hand, higher levels of linoleic acid (LA), another type of fatty acid, were linked to an increased risk of acne. Interestingly, the connection between LA and acne risk was influenced by genetic variations related to a specific gene (FADS1), which plays a role in fatty acid metabolism.
Overall, this study sheds light on how omega-3 fatty acids, particularly DHA, could provide a protective effect against acne. This finding could influence future dietary recommendations for those seeking to manage or prevent acne more effectively.
Our findings highlighted that higher levels of DHA were associated with a lower risk of acne. Specifically, a significant reduction in acne risk was observed with increased DHA levels and its ratio to total fatty acids. On the other hand, higher levels of linoleic acid (LA), another type of fatty acid, were linked to an increased risk of acne. Interestingly, the connection between LA and acne risk was influenced by genetic variations related to a specific gene (FADS1), which plays a role in fatty acid metabolism.
Overall, this study sheds light on how omega-3 fatty acids, particularly DHA, could provide a protective effect against acne. This finding could influence future dietary recommendations for those seeking to manage or prevent acne more effectively.
8.8
Skin quality improvement
Most Useful Review
I first purchased fish oil for its cost-effectiveness and lemon flavour. I was pleasantly surprised by how comfortable I felt and noticed an improvement in my skin quality, which had been prone to acne due to my meat-heavy diet. The subtle lemon aroma made it easy to consume, and the packaging is appealing. It seems to be an essential supplement for me.
Vitamin E
7
Vitamin E levels lower in acne
Serum vitamin E levels and chronic inflammatory skin diseases: A systematic review and meta-analysis.
Most Relevant Research
We examined the relationship between serum vitamin E levels and acne as part of a broader investigation into chronic inflammatory skin diseases. Our analysis included a number of studies that focused on vitamin E in patients, comparing their serum levels with those of healthy individuals.
The findings revealed that patients with acne had significantly lower levels of serum vitamin E compared to controls. This supports the idea that vitamin E might play a role in skin health, although we must note that the study did not delve into how vitamin E treatment specifically improves acne.
In short, while the lower vitamin E levels in acne patients are noteworthy, the study leaves us without conclusive evidence of vitamin E’s direct impact on treating acne. We highlight the importance of evaluating vitamin E status as part of managing skin health across various conditions, including acne.
The findings revealed that patients with acne had significantly lower levels of serum vitamin E compared to controls. This supports the idea that vitamin E might play a role in skin health, although we must note that the study did not delve into how vitamin E treatment specifically improves acne.
In short, while the lower vitamin E levels in acne patients are noteworthy, the study leaves us without conclusive evidence of vitamin E’s direct impact on treating acne. We highlight the importance of evaluating vitamin E status as part of managing skin health across various conditions, including acne.
10
No acne experienced
Most Useful Review
Excellent vitamins! I'm very satisfied as my skin is now radiant. I had persistent acne before, but after three weeks of taking these vitamins, I no longer had any at all.
Biotin
8
Biotin's role in acne therapy
Probiotic supplement combined with topical therapy in the treatment of mild to moderate acne: results from an Italian single centre interventional study.
Most Relevant Research
We explored the potential of combining an oral biotin supplement with a topical gel in addressing mild to moderate acne. Our research focused on understanding whether this innovative treatment approach could provide better results than traditional therapies, which often come with side effects.
In our study, we treated participants with a specially formulated supplement containing biotin and three strains of lactic ferments, alongside a topical gel that included azelaic acid, hydroxypinacolone retinoate, and α-hydroxy acids. After 60 days of treatment, we observed notable improvements among the patients.
While we did not solely evaluate the isolated effects of biotin, our findings indicate that combining it with topical treatments may hold promise for managing acne symptoms. However, we must acknowledge that more focused research is necessary to pinpoint the direct impact of biotin itself on acne specifically.
In our study, we treated participants with a specially formulated supplement containing biotin and three strains of lactic ferments, alongside a topical gel that included azelaic acid, hydroxypinacolone retinoate, and α-hydroxy acids. After 60 days of treatment, we observed notable improvements among the patients.
While we did not solely evaluate the isolated effects of biotin, our findings indicate that combining it with topical treatments may hold promise for managing acne symptoms. However, we must acknowledge that more focused research is necessary to pinpoint the direct impact of biotin itself on acne specifically.
9.5
Cleared red spots
Most Useful Review
Excellent! I chose high-dose biotin for the best results. After two weeks, the red spots on my face have disappeared, possibly from acne. This supplement has also benefited my hair, nails, and skin, and I recommend it!
